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Information on EC 1.14.11.26 - deacetoxycephalosporin-C hydroxylase

for references in articles please use BRENDA:EC1.14.11.26

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IUBMB Comments

Requires iron(II). The enzyme can also use 3-exomethylenecephalosporin C as a substrate to form deacetoxycephalosporin C, although more slowly . In Acremonium chrysogenum, the enzyme forms part of a bifunctional protein along with EC 1.14.20.1, deactoxycephalosporin-C synthase. It is a separate enzyme in Streptomyces clavuligerus.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

Synonyms
deacetoxycephalosporin c hydroxylase, deacetylcephalosporin c synthase, daoc hydroxylase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
deacetoxycephalosporin C + 2-oxoglutarate + O2 = deacetylcephalosporin C + succinate + CO2
show the reaction diagram
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