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Information on EC 1.14.13.163 - 6-hydroxy-3-succinoylpyridine 3-monooxygenase

for references in articles please use BRENDA:EC1.14.13.163

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IUBMB Comments

The enzyme catalyses a reaction in the nicotine degradation pathway of Pseudomonas species. One of the enzymes from the soil bacterium Pseudomonas putida S16 contains an FAD cofactor .

The enzyme appears in viruses and cellular organisms

Synonyms
hsp hydroxylase, 6-hydroxy-3-succinoylpyridine hydroxylase, nicotine hydroxylase, nadh-dependent hsp hydroxylase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + 2 NADH + 2 H+ + O2 = 2,5-dihydroxypyridine + succinate semialdehyde + 2 NAD+ + H2O
show the reaction diagram
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