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Information on EC 1.14.13.33 - 4-hydroxybenzoate 3-monooxygenase [NAD(P)H]

for references in articles please use BRENDA:EC1.14.13.33

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IUBMB Comments

A flavoprotein (FAD). The enzyme from Corynebacterium cyclohexanicum is highly specific for 4-hydroxybenzoate, but uses NADH and NADPH at approximately equal rates (cf. EC 1.14.13.2 4-hydroxybenzoate 3-monooxygenase). It is less specific for NADPH2 than EC 1.14.13.2.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
4-hydroxybenzoate-3-hydroxylase, xcc0356, 4hb 3-hydroxylase, nadph-dependent phbh, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O
show the reaction diagram
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