Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
aerobic Mg-protoporphyrin IX monomethyl ester cyclase
Crd1 protein
Chlamydomonas reinhardtii, first identified as gene in response to copper deficiency, one of two isozymes
Cth1 protein
copper target homolog 1, isoenzyme to Crd1
cyclase, magnesium protoporphyrin IX monomethyl ester
-
-
-
-
LCAA
-
a subunit of the Mg protoporphyrin monomethylester cyclase which is required for the stability of the enzyme
LOC_Os01g17170
locus name
magnesium protoporphyrin IX monomethyl ester cyclase
-
magnesium protoporphyrin monomethylester oxidative cyclase
-
-
magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
magnesium-protoporphyrin IX monomethyl ester cyclase
magnesium-protoporphyrin-IX monomethyl ester cyclase
-
-
-
-
magnesium-protoporphyrin-IX monomethyl ester oxidative cyclase
-
-
-
-
Mg protoporphyrin monomethylester cyclase
Mg-protoporphyrin IX methyl ester cyclase
-
Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase
-
-
-
-
Mg-protoporphyrin IX monomethyl ester cyclase
Mg-protoporphyrin IX monomethylester cyclase system
-
-
Mg-protoporphyrin monomethylester cyclase
MgPME oxidative cyclase
-
O2-dependent Mg-protoporphyrin monomethyl ester cyclase
-
oxygen-dependent Mg-protoporphyrin IX monomethylester cyclase system
-
-
oxygen-independent Mg-protoporphyrin IX monomethylester cyclase system
-
-
rice copper response defect 1
i.e. OsCRD1, a putative subunit of enzyme MPEC
AcsF
-
AcsF
gammaproteobacteria NOR51-B
-
-
-
AcsF
Roseibium alexandrii
-
AcsF
Roseibium alexandrii DFL-11
-
-
AcsF protein
-
AcsF protein
previously named orf358
aerobic Mg-protoporphyrin IX monomethyl ester cyclase
-
aerobic Mg-protoporphyrin IX monomethyl ester cyclase
-
BChE
-
-
CHL27
-
CHL27
-
a subunit of the Mg protoporphyrin monomethylester cyclase which is required for the enzyme reaction
CHL27 protein
-
CHL27 protein
Arabidopsis thaliana
CRD1
-
magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
-
magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
-
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
magnesium-protoporphyrin IX monomethyl ester cyclase
-
Mg protoporphyrin monomethylester cyclase
-
Mg protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin IX monomethyl ester cyclase
-
-
Mg-protoporphyrin IX monomethyl ester cyclase
-
Mg-protoporphyrin IX monomethyl ester cyclase
-
Mg-protoporphyrin IX monomethyl ester cyclase
-
Mg-protoporphyrin IX monomethyl ester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
gammaproteobacteria NOR51-B
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
Roseibium alexandrii
-
Mg-protoporphyrin monomethylester cyclase
Roseibium alexandrii DFL-11
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
A6FPX8
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
-
Mg-protoporphyrin monomethylester cyclase
-
Mg-protoporphyrin monomethylester cyclase
-
-
MgPME cyclase
-
MPEC
-
-
MPEC gene product
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
divinylprotochlorophyllide + NADP+ + 2 H2O
magnesium-mesoporphyrin IX + NADPH + O2
diethyl protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX + NADPH + O2
? + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
magnesium-protochlorophyllide + NADP+ + H2O
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
magnesium-protoporphyrin monomethyl ester + NADPH + H+ + O2
magnesium-divinyl-protochlorophyllide a + NADP+ + H2O
Mg-protoporphyrin IX monomethyl ester + O2 + NADPH + H+
Mg-protochlorophyllide + NADP+ + H2O
additional information
?
-
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
divinylprotochlorophyllide + NADP+ + 2 H2O
-
-
-
?
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
divinylprotochlorophyllide + NADP+ + 2 H2O
-
-
-
-
?
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
divinylprotochlorophyllide + NADP+ + 2 H2O
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
overall reaction
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
overall reaction
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
overall reaction
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
magnesium-protochlorophyllide + NADP+ + H2O
-
-
-
ir
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
magnesium-protochlorophyllide + NADP+ + H2O
the enzyme is involved in the chlorophyll biosynthesis
-
-
ir
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
gammaproteobacteria NOR51-B
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
Roseibium alexandrii
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
Roseibium alexandrii DFL-11
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
A6FPX8
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin monomethyl ester + NADPH + H+ + O2
magnesium-divinyl-protochlorophyllide a + NADP+ + H2O
bacteria are grown under anaerobic (dark green culture color) or semiaerobic (orange-red culture color) conditions and express the enzyme genes under both conditions to similar levels, though the enzyme is normally working under aerobic conditions
-
-
?
magnesium-protoporphyrin monomethyl ester + NADPH + H+ + O2
magnesium-divinyl-protochlorophyllide a + NADP+ + H2O
bacteria are grown under anaerobic (dark green culture color) or semiaerobic (orange-red culture color) conditions and express the enzyme genes under both conditions to similar levels, though the enzyme is normally working under aerobic conditions
-
-
?
Mg-protoporphyrin IX monomethyl ester + O2 + NADPH + H+
Mg-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
Mg-protoporphyrin IX monomethyl ester + O2 + NADPH + H+
Mg-protochlorophyllide + NADP+ + H2O
-
disruption of the bchE gene leads to accumulation of Mg-protoporphyrin IX monomethyl ester and the divinyl form of Mg-protoporphyrin IX monomethyl ester
-
-
?
additional information
?
-
-
overview: tetrapyrrole with substituents at various positions
-
-
?
additional information
?
-
-
overview: tetrapyrrole with substituents at various positions
-
-
?
additional information
?
-
-
the enzyme is involved in the chlorophyll biosynthetic pathway, the chlorophyll biosynthetic intermediates Mg-protoporphyrin IX and Mg-protoporphyrin IX monomethyl ester are used as a signal molecules in the chloroplast-to-nucleus signal transduction for regulation of nucleus-located Lhc genes encoding chlorophyll a/b binding proteins of the light-harvesting complex
-
-
?
additional information
?
-
in vitro cyclase activity is obtained with recombinant XanL in combination with ferredoxin (Fd) and ferredoxin-NADPH oxidoreductase (FNR). Fd and FNR are plastid-localized redox components. Enzymatic assays combining spinach Fd and FNR with XanL[coYcf54] show high activity
-
-
-
additional information
?
-
-
in vitro cyclase activity is obtained with recombinant XanL in combination with ferredoxin (Fd) and ferredoxin-NADPH oxidoreductase (FNR). Fd and FNR are plastid-localized redox components. Enzymatic assays combining spinach Fd and FNR with XanL[coYcf54] show high activity
-
-
-
additional information
?
-
-
the enzyme converts Mg-protoporphyrin IX monomethyl ester into protochlorophylide, a reaction of the bacteriochlorophyll biosynthetic pathway
-
-
?
additional information
?
-
-
the enzyme converts Mg-protoporphyrin IX monomethyl ester into protochlorophylide
-
-
?
additional information
?
-
-
AcsF and BchE perform incorporation of an oxygen atom from molecular oxygen and water into the C-13 position of Mg-protoporphyrin IX monomethylester, respectively. ChlAI is the sole MPE cyclase system under aerobic conditions and the induced ChlAII operates together with ChlAI under micro-oxic conditions
-
-
?
additional information
?
-
transformation of the side chain of magnesium protoporphyrin IX monomethyl ester cyclase (MgPMe)
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
divinylprotochlorophyllide + NADP+ + 2 H2O
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
magnesium-protochlorophyllide + NADP+ + H2O
the enzyme is involved in the chlorophyll biosynthesis
-
-
ir
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
magnesium-protoporphyrin monomethyl ester + NADPH + H+ + O2
magnesium-divinyl-protochlorophyllide a + NADP+ + H2O
Mg-protoporphyrin IX monomethyl ester + O2 + NADPH + H+
Mg-protochlorophyllide + NADP+ + H2O
-
disruption of the bchE gene leads to accumulation of Mg-protoporphyrin IX monomethyl ester and the divinyl form of Mg-protoporphyrin IX monomethyl ester
-
-
?
additional information
?
-
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
divinylprotochlorophyllide + NADP+ + 2 H2O
-
-
-
-
?
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
divinylprotochlorophyllide + NADP+ + 2 H2O
-
-
-
-
?
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
divinylprotochlorophyllide + NADP+ + 2 H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
overall reaction
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
overall reaction
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
overall reaction
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + H+ + O2
protochlorophyllide a + NADP+ + H2O
-
intermediates are 6-beta-hydroxy analogue and 6-beta-oxo analogue of protochlorophyllide a
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
gammaproteobacteria NOR51-B
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
Roseibium alexandrii
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
Roseibium alexandrii DFL-11
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
A6FPX8
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin IX monomethyl ester + NADPH + O2
magnesium-divinyl-protochlorophyllide + NADP+ + H2O
-
-
-
?
magnesium-protoporphyrin monomethyl ester + NADPH + H+ + O2
magnesium-divinyl-protochlorophyllide a + NADP+ + H2O
bacteria are grown under anaerobic (dark green culture color) or semiaerobic (orange-red culture color) conditions and express the enzyme genes under both conditions to similar levels, though the enzyme is normally working under aerobic conditions
-
-
?
magnesium-protoporphyrin monomethyl ester + NADPH + H+ + O2
magnesium-divinyl-protochlorophyllide a + NADP+ + H2O
bacteria are grown under anaerobic (dark green culture color) or semiaerobic (orange-red culture color) conditions and express the enzyme genes under both conditions to similar levels, though the enzyme is normally working under aerobic conditions
-
-
?
additional information
?
-
-
the enzyme is involved in the chlorophyll biosynthetic pathway, the chlorophyll biosynthetic intermediates Mg-protoporphyrin IX and Mg-protoporphyrin IX monomethyl ester are used as a signal molecules in the chloroplast-to-nucleus signal transduction for regulation of nucleus-located Lhc genes encoding chlorophyll a/b binding proteins of the light-harvesting complex
-
-
?
additional information
?
-
-
the enzyme converts Mg-protoporphyrin IX monomethyl ester into protochlorophylide, a reaction of the bacteriochlorophyll biosynthetic pathway
-
-
?
additional information
?
-
transformation of the side chain of magnesium protoporphyrin IX monomethyl ester cyclase (MgPMe)
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
additional information
-
protein YGL8 has the dual functions in chlorophyll biosynthesis: one as a catalytic subunit of MgPME cyclase, the other as a core component of FLU-YGL8-LCAA-POR complex in chlorophyll biosynthesis, physical interaction between YGL8 and a rice chloroplast protein, low chlorophyll accumulation A (OsLCAA). YGL8 also interacts with the other two rice chloroplast proteins, viz. fluorescent (OsFLU1) and NADPH:protochlorophyllide oxidoreductase (OsPORB)
evolution
-
phylogeny of the YL-1 protein family, overview
evolution
the enzyme belongs to the ferritin-like, diiron-carboxylate protein family
evolution
the process for the formation of the unique isocyclic fifth ring of chlorophyll involves the conversion of Mg-protoporphyrin IX monomethyl ester (MgPME) to 3,8-divinyl protochlorophyllide a (DV PChlide a), and it requires incorporation of an oxygen atom, sourced from either water or O2, indicating the existence of two mechanistically different MgPME cyclases. Most anoxygenic phototrophic bacteria utilise an O2-sensitive radical SAM enzyme containing [4Fe-4S] and cobalamin cofactors to catalyse the reaction, while oxygenic phototrophs including cyanobacteria, algae and plants, as well as some purple bacteria, adopt an O2-dependent cyclase for the reaction. Mg-protoporphyrin IX monomethyl ester (MgPME) cyclase catalyses the formation of the isocyclic ring, the hallmark of chlorins and bacteriochlorins, producing protochlorophyllide a and contributing significantly to the absorption properties of chlorophylls and bacteriochlorophylls. Three classes of O2-dependent cyclase have been identified, all with a catalytic subunit AcsF, a putative diiron protein, but they differ in the requirement for an auxiliary subunit, either Ycf54 for the enzyme found in oxygenic phototrophs, or BciE for the alphaproteobacterial enzyme
evolution
two distinct enzymes have been identified that catalyze the cyclase reaction, originally distinguished by the source of the incorporated oxygen. The enzyme that catalyzes the cyclase reaction in the absence of molecular oxygen (anaerobic) derives the oxygen from water and is encoded by bchE in facultative photosynthetic bacteria like Rhodobacter sphaeroides. The anaerobic enzyme functions as a hydratase, whereas the aerobic cyclase is an oxygenase. The aerobic cyclase belongs to the family of diiron carboxylate-bridged proteins characterized by the iron-binding motif E-Xn-E-X-X-H-Xn-E-Xn-E-X-X-H. The cyclase activity requires both additional soluble and membrane-bound fractions
malfunction
a Chl27-antisense Arabidopsis mutant accumulates the cyclase substrate magnesium-protoporphyrin IX monomethyl ester and does not produce protochlorophyllide a
malfunction
a Rubrivivax gelatinosus strain with disrupted acsF gene cannot synthesize bacteriochlorophyll under oxygenated conditions but accumulates the substrate magnesium-protoporphyrin IX monomethyl ester, in contrast, under low-oxygene conditions the phenotype is similar to the wild-type, an alternative pathway for the reaction exists vie the bchE genes
malfunction
crd1 strains fail to accumulate photosystem 1 (PS 1) and light-harvesting complex 1 (LHC 1) during hypoxia or copper deficiency, and have reduced amounts of LHC 2, Crd1 abundance is increased in copper or oxygen deficient cells
malfunction
Cth1 accumulates in copper-sufficient, oxygenated cells
malfunction
the Arabidopsis chl27-t knock-down mutant has a T-DNA insertion within the promoter region reducing mRNA levels dramatically, growth is slowed down and plants look pale due to chloroplast development defects (unstacking of thylakoid membranes), chlorophyll fluorescence analysis shows a low photosynthetic activity, numerous nuclear genes involved in pigment biosynthesis, photosynthesis (light-harvesting complex I and II, photo system I and II), for iron acquisition, carbon fixation, cold acclimation, and for electron carriers are repressed, stress and detoxifying related gene expression is affected most prominently, more than 600 genes are repressed, a similar number of genes are induced
malfunction
-
transgenic tobacco with antisense NTZIP-RNA displays chlorosis and a lack of the ability to turn green under normal growth conditions
malfunction
xantha-l35 and viridis-k deficient mutants grown in the dark, fed with delta-aminolevulinic acid, accumulate the substrate magnesium-protoporphyrin IX monomethyl ester and produce reduced amounts of protochlorophyllide a, in vitro complementation assay with mutants the aerobic cyclase is composed of at least 3 gene products, 1 soluble and 2 membrane-bound proteins (xantha-l and viridian-k)
malfunction
-
deficiency of the LCAA subunit affects Ala synthesis and the accumulation of proteins in tetrapyrrole biosynthesis
malfunction
-
chlorophyll biosynthesis upstream genes are highly expressed in the yl-1 mutant, while downstream genes are compromised, indicating that enzyme MPEC plays a pivotal role in the chlorophyll biosynthesis. The yl-1 mutant shows a yellow leaf and panicle phenotype with reduced chlorophyll accumulation through the whole growth phases. Mutant yl-1 exhibits the temperature-independent yellow leaf phenotype, it presents abnormal chloroplast development and attenuated photosynthetic efficiency. The mutant yl-1 affects mRNA accumulation levels of Chl biosynthesis process
malfunction
decreased CHL27 transcript levels result in a substantial reduction of activity of MgPME cyclase and MgP monomethylester accumulation, in comparison to dexamethasone-treated wild-type seedlings
malfunction
-
Hordeum vulgare mutants viridis-k, light green 3, light green 4 and zebra stripe 2 are not deficient in Ycf54. Both xanthan-l and viridis-k membranes are unable to support MPEC activity when combined with wild-type soluble fraction
malfunction
mutation of in enzyme MPEC causes the pale-green leaf mutant phenotype of mutant m167 with yellow-green leaves across the whole lifespan. Chlorophyll content decreases by 43-51% and the granal stacks of chloroplasts becomes thinner in m167. Chlorophyll fluorescence parameters, including Fv/Fm (the maximum quantum efficiency of PSII) and quantum yield of PSII (Y(II)), are lower in m167 than those in wild-type plants, and photosynthesis rate decreases by 40% in leaves of m167 mutant compared with wild-type plants, which leads to yield reduction in m167
malfunction
-
Oryza sativa yellow-green leaf 8 (ygl8) mutant exhibits a chlorosis phenotype with abnormal chloroplast development in young leaves. During the development of leaves, the chlorotic plants turn green accompanied by restorations in chlorophyll content and chloroplast ultrastructure, expression levels of some nuclear genes associated with Chl biosynthesis are affected in both the ygl8 mutant and YGL8 RNA interference lines. YGL8 expression demonstrates no differences between the wild-type and ygl8 mutant plants, but the mutant shows increase of Proto IX and MgP/MgPME expression, accompanied with the decrease of protochlorophyllide. Phenotype, overview
malfunction
the Ycf54 protein forms a complex with the component of the oxidative cyclase, Sll1214 (CycI, gene slr1780). Partial inactivation of the ycf54 gene leads to chlorophyll deficiency in cyanobacteria and plants, and the complete deletion of the ycf54 gene in the cyanobacterium Synechocystis 6803 results accumulation of huge concentrations of the cyclase substrate MgPME together with 3-formyl MgPME, in the DELTAycf54 strain. The Ycf54 protein is important, but not essential, for activity of the oxidative cyclase. Phenotype, overview
malfunction
the yellow and spotted leaf 1 (ysl1) mutant in rice exhibits a yellow-green leaf phenotype throughout the whole developmental stage and a spotted leaf phenotype at seedling and tillering stages. The phenotype of ysl1 is caused by a single nucleotide substitution of Mg-protoporphyrin IX monomethyl ester cyclase YSL1 which is allelic to YGL8, OsCRD1, and YL-1
metabolism
enzyme is involved in the protochlorophyllide a synthesis
metabolism
-
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
-
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
-
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
-
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
protochlorophyllide a production (formation of the isocyclic ring) via several intermediates in the chlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
Roseibium alexandrii
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
metabolism
in the chlorophyll biosynthesis pathway the formation of protochlorophyllide is catalyzed by Mg-protoporphyrin IX methyl ester (MgPME) cyclase. The requirement for de novo chlorophyll molecules differs completely for each chlorophyll-binding protein
metabolism
in the first unique step of the chlorophyll biosynthetic pathway, Mg2+ is inserted into protoporphyrin IX. Subsequently, a methyl group is transferred to the carboxyl group of the propionate on the C ring of Mg-protoporphyrin IX, generating Mg-protoporphyrin IX monomethyl ester (MPE), which is the substrate of the MPE cyclase. The cyclase catalyzes the formation of the isocyclic E ring by insertion of oxygen and attaching the methylated propionate to the methene bridge between pyrrole rings C and D, forming protochlorophyllide. Chlorophyll is obtained after additional reactions involving a light-dependent oxidation of protochlorophyllide to chlorophyllide, reduction of the vinyl group on the B ring, and, finally, addition of a polyisoprene tail
metabolism
Mg-protoporphyrin IX monomethyl ester cyclase (MPEC) plays an essential role in chlorophyll biosynthesis
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
Roseibium alexandrii DFL-11
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
gammaproteobacteria NOR51-B
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
metabolism
-
magnesium-protoporphyrin IX monomethylester cyclase is one of the key enzymes of the bacteriochlorophyll biosynthesis pathway
-
physiological function
-
an essential enzyme during chlorophyll (Chl) biosynthesis. The enzyme subunit protein YL-1 is required for plastid membrane stability. The formation of the isocyclic ring is an aerobic reaction catalyzed by MPEC in chloroplasts, which controls the conversion of magnesium-protoporphyrin IX 13-monomethyl ester to divinyl protochlorophyllide (DVpchlide). The function of YL-1 in MPEC complex is essential for normal chlorophyll biosynthesis
physiological function
-
enzyme MPEC requires components found in both the membrane and soluble fractions of the chloroplast. It requires components associated with the plastid membrane and the plastid soluble fraction for activity. One of the components, XanL is found associated with the membrane and another protein, Ycf54 has been identified based upon its strong association of with XanL. The conserved chloroplast polypeptide Ycf54 is involved in the MPEC-enzyme catalyzed reaction
physiological function
MPEC is an essential enzyme in chlorophyll biosynthesis
physiological function
the enzyme catayzes the transformation of a side chain of magnesium protoporphyrin IX monomethyl ester cyclase (MgPMe)
physiological function
cyclic tetrapyrroles, are among the most abundant natural pigments on Earth. They are the major absorbers of the solar energy that drives photosynthesis, and billions of tonnes of chlorophyll are synthesised annually on land and in the oceans. The decisive biosynthetic step that determines the absorption properties of chlorophyll, and more visually its green color, is the formation of the unique isocyclic fifth ring. This process involves the conversion of Mg-protoporphyrin IX monomethyl ester (MgPME) to 3,8-divinyl protochlorophyllide a (DV PChlide a), and it requires incorporation of an oxygen atom, sourced from either water or O2, indicating the existence of two mechanistically different MgPME cyclases. Most anoxygenic phototrophic bacteria utilise an O2-sensitive radical SAM enzyme containing [4Fe-4S] and cobalamin cofactors to catalyse the reaction, while oxygenic phototrophs including cyanobacteria, algae and plants, as well as some purple bacteria, adopt an O2-dependent cyclase for the reaction. Mg-protoporphyrin IX monomethyl ester (MgPME) cyclase catalyses the formation of the isocyclic ring, the hallmark of chlorins and bacteriochlorins, producing protochlorophyllide a and contributing significantly to the absorption properties of chlorophylls and bacteriochlorophylls. The diiron cluster within AcsF is reduced by ferredoxin furnished by NADPH and ferredoxin:NADP+ reductase or by direct coupling to Photosystem I photochemistry, linking cyclase to the photosynthetic electron transport chain
physiological function
Mg-protoporphyrin IX monomethyl ester cyclase (MPEC) plays an essential role in chlorophyll biosynthesis
physiological function
the Xantha-l gene product (XanL) is a membrane-bound diiron monooxygenase, which requires additional soluble and membrane-bound components for its activity. The enzyme XanL is a Mg-protoporphyrin IX monomethyl ester cyclase involved in the formation of the isocyclic E-ring characteristic of chlorophylls. The MPE cyclase is a ferredoxin-dependent enzyme. Ferredoxin is part of the photosynthetic electron-transport chain, which suggests that the cyclase reaction might be connected to photosynthesis under light conditions
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
N182S
-
the ygl8 mutation causes a conserved amino acid substitution, which is related to the alterations of chlorophyll precursor content
A96T
site-directed mutagenesis, the point mutation in OsCRD1 does not change its location, but leads to deficiency in chlorophyll biosynthesis and chloroplast development and decreases photosynthetic capacity in rice, phenotype
G286A
naturally occurring mutation, the mutation in enzyme MPEC causes the phenotype of the rice pale-green leaf mutant m167, phenotype
additional information
mutant plants are complemented with enzyme construct fused to GFP at C-terminus under native promoter or a constitutive 35S-promoter control, suppressing the mutant phenotype, N-terminal deletion of the first 39 amino acids leads to location in the cytosol instead of chloroplast membrane (crucial localization signal)
additional information
silencing of gene CHL27 by siRNA overexpression, encoding the CHLH subunit of enzyme Mg protoporphyrin monomethylester cyclase, for more than 24 h results in necrotic leaf lesions and modulated transcript levels of oxidative stress-responsive and photosynthesis-associated nuclear genes (PhANGs), transcriptome analysis, phenotypes, overview
additional information
construction of xantha-l35, xantha-l81, xantha-l82, viridis-k23, and viridis-k170 mutants, the mutants are all inactive in cyclase activity, phenotypes of mutant plants, overview
additional information
-
construction of xantha-l35, xantha-l81, xantha-l82, viridis-k23, and viridis-k170 mutants, the mutants are all inactive in cyclase activity, phenotypes of mutant plants, overview
additional information
-
identification of a xantha-l mutant, defective in a gene of Mg-protoporphyrin monomethyl ester cyclase, the mutant does not show the gun mutant phenotype, that is defective in the chloroplast-to-nucleus signal transduction and expresses Lhc even when chloroplast development is inhibited by the herbicide norflurazon, the xantha-181 mutant can synthesize Mg-protoporphyrin IX and Mg-protoporphyrin IX monomethyl ester, phenotype, overview
additional information
-
generation of subunit YL-1 mutants yl-1, phenotype, overview. The yl-1 mutant shows a yellow leaf and panicle phenotype with reduced chlorophyll accumulation through the whole growth phases. Mutant yl-1 exhibits the temperature-independent yellow leaf phenotype, it presents abnormal chloroplast development and attenuated photosynthetic efficiency
additional information
-
isolation of an Oryza sativa yellow-green leaf 8 (ygl8) mutant that exhibits chlorosis phenotype with abnormal chloroplast development in young leaves. During the development of leaves, the chlorotic plants turn green accompanied by restorations in chlorophyll content and chloroplast ultrastructure. Expression levels of some nuclear genes associated with Chl biosynthesis are affected in both the ygl8 mutant and YGL8 RNA interference lines. Phenotype, overview. Ygl8 knockout by RNAi
additional information
mutant m167 is isolated from a EMS mutagenized population from the Japonica rice variety Kitaake. To construct the F2 mapping population, the yellow-green leaf rice mutant m167 is crossed with rice varieties Zhefu802 and Dular, respectively, genotyping of F2 population
additional information
yellow and spotted leaf 1 (ysl1) mutant in rice exhibiting a yellow-green leaf phenotype throughout the whole developmental stage and a spotted leaf phenotype at seedling and tillering stages. Genetic analysis indicates that a single recessive gene is responsible for the phenotype of ysl1 mutant. Map-based cloning shows that the mutation site is located at the region of 105.4-kb between RM572 and L3 on the short arm of chromosome 1. Sequence analysis reveals that a point mutation (C-to-T) happens in the coding region of candidate gene YSL1 (LOC_Os01g17170) which causes an amino acid change in MPEC. Mutant phenotype analysis. Growing under natural conditions, ysl1 mutant exhibits a yellow-green leaf in the whole developmental stage and slow growth comparing with its wild-type. Besides, the spots appear in the leaves of the mutant at seedling and tillering stages, are reduced at heading stage, and disappear at mature stage. Most of the main agronomic traits significantly decrease in the mutant. For example, plant height, number of productive panicles per plant, number of spikelets per panicle, seed setting rate, and 1000 grain weight decrease by 16.8%, 20.7%, 17.8%, 7.3%, and 10.6%, respectively, while the days to heading significantly increase by 12.1%
additional information
chlorophyll fluorescence analysis of Arabidopsis wild-type Col-0 and PeMPEC transgenic plants, overview
additional information
-
chlorophyll fluorescence analysis of Arabidopsis wild-type Col-0 and PeMPEC transgenic plants, overview
additional information
-
the lack of the BluB protein function in Rhodospirillum rubrum is reflected by the impaired ability of a DELTAbluB strain to synthesize cobalamin and to convert Mg-protoporphyrin IX monomethyl ester into protochlorophylide catalyzed by the MPE-cyclase enzyme, phenotype, overview
additional information
-
construction of a mutants lacking chlAI, chlAII, slr0905, sll1242, or slr0309, respectively, the DELTAchlAI mutant fails to grow under aerobic conditions with anomalous accumulation of a pigment with fluorescence emission peak at 595 nm, the growth defect is restored by the cultivation under oxygen-limited micro-oxic conditions. MPE accumulation is also detected in DELTAchlAII mutant grown under microoxic conditions, but not in any of the bchE mutants. The phenotype is consistent with the expression pattern of two chlA genes: chlAII was induced under micro-oxic conditions in contrast to the constitutive expression of chlAI, phenotypes, overview
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Bollivar, D.W.; Beale, S.I.
The chlorophyll biosynthetic enzyme Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase. Characterization and partial purification from Chlamydomonas reinhardtii and Synechocystis sp. PCC 6803
Plant Physiol.
112
105-114
1996
Synechocystis sp., Chlamydomonas reinhardtii
brenda
Walker, C.J.; Castelfranco, P.A.; Whyte, B.J.
Synthesis of divinyl protochlorophyllide. Enzymological properties of the magnesium-protoporphyrin IX monomethyl ester oxidative cyclase system
Biochem. J.
276
691-697
1991
Cucumis sativus
-
brenda
Walker, C.J.; Mansfield, K.E.; Rezzano, I.N.; Hanamoto, C.M.; Smith, K.M.; Castelfranco, P.A.
The magnesium-protoporphyrin IX (oxidative) cyclase system. Studies on the mechanism and specificity of the reaction sequence
Biochem. J.
255
685-692
1988
Cucumis sativus
brenda
Whyte, B.J.; Castelfranco, P.A.
Further observations on the magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase system
Biochem. J.
290
355-359
1993
Cucumis sativus
-
brenda
Wong, Y.S.; Castelfranco, P.A.
Resolution and reconstitution of magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase, the enzyme system responsible for the formation of the chlorophyll isocyclic ring
Plant Physiol.
75
658-661
1984
Cucumis sativus
brenda
Fuesler, T.P.; Wong, Y.S.; Castelfranco, P.A.
Localization of magnesium-chelatase and magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activities within isolated, developing cucumber chloroplasts
Plant Physiol.
75
662-664
1984
Cucumis sativus
brenda
Wong, Y.S.; Castelfranco, P.A.
Properties of the magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase system
Plant Physiol.
79
730-733
1985
Cucumis sativus
brenda
Gadjieva, R.; Axelsson, E.; Olsson, U.; Hansson, M.
Analysis of gun phenotype in barley magnesium chelatase and Mg-protoporphyrin IX monomethyl ester cyclase mutants
Plant Physiol. Biochem.
43
901-908
2005
Hordeum vulgare
brenda
Rzeznicka, K.; Walker, C.J.; Westergren, T.; Kannangara, C.G.; von Wettstein, D.; Merchant, S.; Gough, S.P.; Hansson, M.
Xantha-l encodes a membrane subunit of the aerobic Mg-protoporphyrin IX monomethyl ester cyclase involved in chlorophyll biosynthesis
Proc. Natl. Acad. Sci. USA
102
5886-5891
2005
Hordeum vulgare (Q5EFU4), Hordeum vulgare
brenda
Minamizaki, K.; Mizoguchi, T.; Goto, T.; Tamiaki, H.; Fujita, Y.
Identification of two homologous genes, chlAI and chlAII, that are differentially involved in isocyclic ring formation of chlorophyll a in the Cyanobacterium Synechocystis sp. PCC 6803
J. Biol. Chem.
283
2684-2692
2008
Synechocystis sp. PCC 6803
brenda
Gough, S.P.; Rzeznicka, K.; Peterson Wulff, R.; Francisco, J.d.; Hansson, A.; Jensen, P.E.; Hansson, M.
A new method for isolating physiologically active Mg-protoporphyrin monomethyl ester, the substrate of the cyclase enzyme of the chlorophyll biosynthetic pathway
Plant Physiol. Biochem.
45
932-936
2007
Rhodobacter capsulatus
brenda
Gray, M.J.; Escalante-Semerena, J.C.
Single-enzyme conversion of FMNH2 to 5,6-dimethylbenzimidazole, the lower ligand of B12
Proc. Natl. Acad. Sci. USA
104
2921-2926
2007
Rhodospirillum rubrum
brenda
Tang, K.H.; Wen, J.; Li, X.; Blankenship, R.E.
Role of the AcsF protein in Chloroflexus aurantiacus
J. Bacteriol.
191
3580-3587
2009
Chloroflexus aurantiacus (A9WIR9), Chloroflexus aurantiacus, Chloroflexus aurantiacus J-10-fl (A9WIR9)
brenda
Liu, H.; Zheng, C.
MPEC: An important gene in the chlorophyll biosynthesis pathway in photosynthetic organisms
Photosynthetica
46
321-328
2008
Cucumis sativus, Nicotiana tabacum, Oryza sativa, Rosa davurica, Rubrivivax gelatinosus (P0DJN9), Ipomoea nil (Q40093), Hordeum vulgare (Q5EFU4), Trifolium repens (Q7XJI1), Brassica napus (Q7XJI2), Salix babylonica (Q7XJI4), Spinacia oleracea (Q7XJI5), Triticum aestivum (Q7XJI6), Chlamydomonas reinhardtii (Q9AR22), Chlamydomonas reinhardtii (Q9LD46), Arabidopsis thaliana (Q9M591)
-
brenda
Bang, W.Y.; Jeong, I.S.; Kim, D.W.; Im, C.H.; Ji, C.; Hwang, S.M.; Kim, S.W.; Son, Y.S.; Jeong, J.; Shiina, T.; Bahk, J.D.
Role of Arabidopsis CHL27 protein for photosynthesis, chloroplast development and gene expression profiling
Plant Cell Physiol.
49
1350-1363
2008
Arabidopsis thaliana (Q9M591)
brenda
Boldareva-Nuianzina, E.N.; Blahova, Z.; Sobotka, R.; Koblizek, M.
Distribution and origin of oxygen-dependent and oxygen-independent forms of Mg-protoporphyrin monomethylester cyclase among phototrophic proteobacteria
Appl. Environ. Microbiol.
79
2596-2604
2013
Bradyrhizobium sp., Methylobacterium sp., Cereibacter sphaeroides, Rhodomicrobium vannielii, Rhodopseudomonas palustris, Sphingomonas sp., Roseovarius sp., Roseovarius sp. (A3VXW7), Methylobacterium radiotolerans, Methylocella silvestris, Roseobacter litoralis, gammaproteobacteria, Citromicrobium bathyomarinum, Limnohabitans sp., Roseibium alexandrii (A0A5E8GWV2), Yoonia vestfoldensis (A3V2J0), Erythrobacter sp. (A3WHT4), Congregibacter litoralis (A4ACN5), Roseobacter sp. (A4EGS5), Roseobacter sp. (A6FPX8), Dinoroseobacter shibae (A8LQ37), Hoeflea phototrophica (A9DA86), Methylorubrum populi (B1ZBN5), Rhodospirillum centenum (B6ITV8), Methylorubrum extorquens (C5AV79), Rhodobacter sp. (C8RYM0), Brevundimonas subvibrioides (D9QPB7), Ahrensia sp. R2A130 (E0MPX4), Acidiphilium multivorum (F0IZP3), Rubrivivax benzoatilyticus (F3LQD6), Methyloversatilis universalis (F5RI16), gamma proteobacterium HIMB55 (H3NRI3), Rubrivivax gelatinosus (I0HUK7), Agrobacterium albertimagni (K2PJ79), Roseobacter denitrificans (Q16DS9), Jannaschia sp. CCS1 (Q28W44), Agrobacterium albertimagni AOL15 (K2PJ79), Bradyrhizobium sp. ORS278, Methyloversatilis universalis FAM5 (F5RI16), Methylorubrum populi BJ001 (B1ZBN5), Bradyrhizobium sp. BTAi1, Methylorubrum extorquens ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1 (C5AV79), gammaproteobacteria NOR5-3, Yoonia vestfoldensis SKA53 (A3V2J0), Rubrivivax benzoatilyticus JA2 (F3LQD6), Rubrivivax gelatinosus IL144 (I0HUK7), Acidiphilium multivorum AIU301 (F0IZP3), Dinoroseobacter shibae DFL 12 (A8LQ37), Roseobacter sp. AzwK-3b (A6FPX8), Brevundimonas subvibrioides ATCC 15264 (D9QPB7), Methylocella silvestris BL2, Roseovarius sp. TM1035, Citromicrobium bathyomarinum JL354, Roseibium alexandrii DFL-11 (A0A5E8GWV2), gammaproteobacteria NOR51-B, Hoeflea phototrophica DFL-43 (A9DA86), Roseobacter litoralis Och 149c, gammaproteobacteria HTCC2080, Limnohabitans sp. Rim28, Congregibacter litoralis KT71 (A4ACN5), Limnohabitans sp. Rim47, Erythrobacter sp. NAP1 (A3WHT4), Rhodomicrobium vannielii ATCC 17100, Methylobacterium sp. 4-46, Roseovarius sp. 217 (A3VXW7), Roseobacter sp. CCS2 (A4EGS5)
brenda
Hollingshead, S.; Kopeca, J.; Jackson, P.; Canniffe, D.; Davison, P.; Dickman, M.; Sobotkas, R.; Hunter, C.
Conserved chloroplast open-reading frame ycf54 is required for activity of the magnesium protoporphyrin monomethylester oxidative cyclase in Synechocystis PCC 6803
J. Biol. Chem.
287
27823-27833
2012
Synechocystis sp.
brenda
Albus, C.A.; Salinas, A.; Czarnecki, O.; Kahlau, S.; Rothbart, M.; Thiele, W.; Lein, W.; Bock, R.; Grimm, B.; Schoettler, M.A.
LCAA, a novel factor required for magnesium protoporphyrin monomethylester cyclase accumulation and feedback control of aminolevulinic acid biosynthesis in tobacco
Plant Physiol.
160
1923-1939
2012
Nicotiana tabacum
brenda
Lakshmi, K.; Suresha, G.
Molecular cloning and sequence analysis of novel aerobic cyclase system, Fe-containing subunit (ACSF) coding gene from Erianthus arundinaceus
Ann. Biol.
30
15-20
2014
Tripidium arundinaceum (R9VYS6)
-
brenda
Bollivar, D.; Braumann, I.; Berendt, K.; Gough, S.P.; Hansson, M.
The Ycf54 protein is part of the membrane component of Mg-protoporphyrin IX monomethyl ester cyclase from barley (Hordeum vulgare L.)
FEBS J.
281
2377-2386
2014
Hordeum vulgare
brenda
Hollingshead, S.; Kopecna, J.; Armstrong, D.; Bucinska, L.; Jackson, P.; Chen, G.; Dickman, M.; Williamson, M.; Sobotka, R.; Hunter, C.
Synthesis of chlorophyll-binding proteins in a fully segregated DELTAycf54 strain of the cyanobacterium Synechocystis PCC 6803
Front. Plant Sci.
7
292
2016
Synechocystis sp. PCC 6803 (P72584), Synechocystis sp. PCC 6803
brenda
Schlicke, H.; Hartwig, A.S.; Firtzlaff, V.; Richter, A.S.; Glaesser, C.; Maier, K.; Finkemeier, I.; Grimm, B.
Induced deactivation of genes encoding chlorophyll biosynthesis enzymes disentangles tetrapyrrole-mediated retrograde signaling
Mol. Plant
7
1211-1227
2014
Arabidopsis thaliana (Q9M591)
brenda
Yang, L.; Lou, Y.; Peng, Z.; Zhao, H.; Sun, H.; Gao, Z.
Molecular characterization and primary functional analysis of PeMPEC, a magnesium-protoporphyrin IX monomethyl ester cyclase gene of bamboo (Phyllostachys edulis)
Plant Cell Rep.
34
2001-2011
2015
Phyllostachys edulis (A0A0K1L5Y4), Phyllostachys edulis
brenda
Kong, W.; Yu, X.; Chen, H.; Liu, L.; Xiao, Y.; Wang, Y.; Wang, C.; Lin, Y.; Yu, Y.; Wang, C.; Jiang, L.; Zhai, H.; Zhao, Z.; Wan, J.
The catalytic subunit of magnesium-protoporphyrin IX monomethyl ester cyclase forms a chloroplast complex to regulate chlorophyll biosynthesis in rice
Plant Mol. Biol.
92
177-191
2016
Oryza sativa
brenda
Wang, X.; Huang, R.; Quan, R.
Mutation in Mg-protoporphyrin IX monomethyl ester cyclase decreases photosynthesis capacity in Rice
PLoS ONE
12
e0171118
2017
Oryza sativa Japonica Group (Q9SDJ2)
brenda
Sheng, Z.; Lv, Y.; Li, W.; Luo, R.; Wei, X.; Xie, L.; Jiao, G.; Shao, G.; Wang, J.; Tang, S.; Hu, P.
Yellow-Leaf 1 encodes a magnesium-protoporphyrin IX monomethyl ester cyclase, involved in chlorophyll biosynthesis in rice (Oryza sativa L.)
PLoS ONE
12
e0177989
2017
Oryza sativa
brenda
Chen, G.E.; Adams, N.B.P.; Jackson, P.J.; Dickman, M.J.; Hunter, C.N.
How the O2-dependent Mg-protoporphyrin monomethyl ester cyclase forms the fifth ring of chlorophylls
Nat. plants
7
365-375
2021
Rubrivivax gelatinosus (P0DJN9), Rubrivivax gelatinosus
brenda
Li, C.; Ma, F.; Jiao, R.; Chen, C.; Wang, Q.; Xiao, F.; Sun, C.; Deng, X.; Dong, C.; Wang, P.
Mutation in Mg-protoporphyrin IX monomethyl ester cyclase causes yellow and spotted leaf phenotype in rice
Plant Mol. Biol. Rep.
37
253-264
2019
Oryza sativa Japonica Group (Q9FTU1)
-
brenda
Stuart, D.; Sandstroem, M.; Youssef, H.M.; Zakhrabekova, S.; Jensen, P.E.; Bollivar, D.W.; Hansson, M.
Aerobic barley Mg-protoporphyrin IX monomethyl ester cyclase is powered by electrons from ferredoxin
Plants (Basel)
9
1157
2020
Hordeum vulgare (Q5EFU4), Hordeum vulgare
brenda