Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
No. of entries

Information on EC 1.8.5.3 - respiratory dimethylsulfoxide reductase

for references in articles please use BRENDA:EC1.8.5.3

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

The enzyme participates in bacterial electron transfer pathways in which dimethylsulfoxide (DMSO) is the terminal electron acceptor. It is composed of three subunits - DmsA contains a bis(guanylyl molybdopterin) cofactor and a [4Fe-4S] cluster, DmsB is an iron-sulfur protein, and DmsC is a transmembrane protein that anchors the enzyme and accepts electrons from the quinol pool. The electrons are passed through DmsB to DmsA and on to DMSO. The enzyme can also reduce pyridine-N-oxide and trimethylamine N-oxide to the corresponding amines with lower activity.

The enzyme appears in viruses and cellular organisms

Synonyms
dmso reductase, dimethyl sulfoxide reductase, dmsor, dmsabc, dimethylsulfoxide reductase, dimethyl sulfoxide/trimethylamine n-oxide reductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
dimethylsulfide + menaquinone + H2O = dimethylsulfoxide + menaquinol
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
-
-, -, -