EC Number |
Inhibitors |
Structure |
---|
1.5.99.4 | hydroxylamine |
22% inhibition at 5 mM |
|
1.5.99.4 | iodoacetamide |
23% inhibition at 10 mM |
|
1.5.99.4 | more |
not inhibited by any intermediates |
|
1.5.99.4 | more |
riboflavin 5'-phosphate protects enzyme against acriflavine inhibition, FMN protects enzyme against acriflavine inhibition, FAD only partially effective, glutathione protects against p-chloromercuriphenylsulfonic inhibition |
|
1.5.99.4 | more |
gene repressor HdnoR binds to the 6hdno gene operator, Kd is 21 nM, and represses enzyme expression, repressor in induced by 6-hydroxy-D-nicotine and 6-hydroxy-L-nicotine in vitro and in vivo |
|
1.5.99.4 | p-chloromercuriphenylsulfonic acid |
62% inhibition at 1 mM |
|
1.5.99.4 | p-hydroxymercuribenzoate |
92% inhibition at 1 mM |
|
1.5.99.4 | Quinacrine |
49% inhibition at 0.1 mM |
|
1.5.99.4 | Tungsten |
inhibitory to enzyme activity, does not inhibit enzyme synthesis |
|