EC Number   |
Application |
Reference |
|---|
    1.8.1.4 | analysis |
development of a blue native-PAGE-based method for isolation of enzymatically active DLDH from animal tissues and visualization as well as quantification of its diaphorase activity using the NADH/nitroblue tetrazolium detection system |
692060 |
| 1.8.1.4 | degradation |
conservation of the Cys-45 residue in human E3 is essential to the efficient catalytic function of the enzyme |
691569 |
| 1.8.1.4 | degradation |
decreased activity of DLDH induced by valproic acid metabolites may, at least in part, account for the impaired rate of oxygen consumption and ATP synthesis in mitochondria if 2-oxoglutarate or glutamate are used as respiratory substrates, thus limiting the flux of these substrates through the citric acid cycle |
691036 |
| 1.8.1.4 | degradation |
DLD is required for hamster acrosome reaction |
691176 |
| 1.8.1.4 | degradation |
N286 and D320 play a role in the catalytic function of the E3 |
674943 |
| 1.8.1.4 | degradation |
S456 and E431 form a catalytic dyad in the DLD monomer, whereas H450, by forming a hydrogen bond with E431, may decrease the ability of E431 to polarize the hydroxyl group of S456 |
694854 |
| 1.8.1.4 | degradation |
shows flavin reductase activity with moderate diaphorase activity |
685693 |
| 1.8.1.4 | degradation |
shows NADH-dependent tellurite reductase activity in vitro |
690755 |
| 1.8.1.4 | degradation |
shows strong diaphorase activity |
685693 |
| 1.8.1.4 | degradation |
T148 is not important to E3 catalytic function, whereas R281 plays a role in the catalytic function of E3 |
693271 |
