EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.1.1.391 | 12alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
Blautia producta |
3beta,12alpha-dihydroxy-5beta-cholan-24-oic acid + NAD+ |
sole pruduct |
? |
1.1.1.391 | 3,12-dioxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
Blautia producta |
3beta-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 3,7-dioxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
Blautia producta |
3beta-hydroxy-7-oxo-5beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
Blautia producta |
3beta,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 7alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
Blautia producta |
3beta,7alpha-dihydroxy-5beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | more |
no activity with 3alpha,7beta-dihydroxy-5beta-cholan-24-oic acid, 3alpha-hydroxy-7-oxo-5beta-cholan-24-oic acid, 3alpha,7beta-dihydroxytaureate, 7,12-dioxo-5beta-cholanate, 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate and 3alpha-hydroxy-7,12-dioxo-5beta-cholanate |
Blautia producta |
? |
- |
? |
1.1.1.391 | 12alpha-hydroxy-3-oxo-5-beta-cholan-24-oic acid + NADH + H+ |
- |
Eggerthella lenta |
3beta,12alpha-dihydroxy-5-beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 12alpha-hydroxy-3-oxo-5-beta-cholan-24-oic acid + NADH + H+ |
- |
Eggerthella lenta ATCC 25559 |
3beta,12alpha-dihydroxy-5-beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 3beta,7alpha-dihydroxy-5beta-cholan-24-oic acid + NAD+ |
i.e. isochenodeoxycholic acid |
Homo sapiens |
7alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
? |
1.1.1.391 | 3beta,7beta-dihydroxy-5beta-cholan-24-oic acid + NAD+ |
substrate docking of isoursodeoxycholic acid to the active site of a three-dimensional model of human class I gammagamma alcohol dehydrogenase reveals that the ADH gammagamma isozyme is the iso bile acid 3beta-hydroxysteroid dehydrogenase present in human liver cytosol, with NAD+ as a cofactor, but ethanol is the preferred substrate |
Homo sapiens |
7beta-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
? |