EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.5.5.1 | electron-transferring flavoprotein + hydroquinone electron transferring flavoprotein + ubiquinol |
- |
Sus scrofa |
semiquinone electron transferring flavoprotein + ubiquinone |
- |
r |
1.5.5.1 | more |
enzyme deficiency leads to glutaric acidemia type II |
Homo sapiens |
? |
- |
? |
1.5.5.1 | more |
genetic regulatory model |
Azospirillum brasilense |
? |
- |
? |
1.5.5.1 | more |
specificity for different ubiquinone derivatives, overview |
Homo sapiens |
? |
- |
? |
1.5.5.1 | more |
assay method uses dichlorophenolindophenol, DCPIP, as substrate |
Drosophila melanogaster |
? |
- |
? |
1.5.5.1 | more |
mechanism of superoxide formation by ETF-QO, reduction potentials of redox centres, overview |
Sus scrofa |
? |
- |
? |
1.5.5.1 | more |
the electron-transferring flavoprotein beta-D128N mutation occurs in a beta-turn located near the AMP binding site, a region that is involved in intersubunit contacts and establishes outer-sphere interactions with the FAD cofactor, namely at the level of the isoalloxazine moiety. Namely ETF b-D128N and ETF b-R191C,would have an impacton reactive oxygen species generation.The ETF variants show about 70% decreased activity in comparison with the wild-type protein, and establish a rationale for their functional defects |
Homo sapiens |
? |
- |
? |
1.5.5.1 | more |
although Agrobacterium tumefaciens ETF-mediated electron transfer to 2,6-DCIP is observed with a number of different dehydrogenases, the reduction of coenzyme Q1 through the DH/ETF/ETF-QO system is only observed with dimethylglycine dehydrogenase, but not with any of the tested Agrobacterium tumefaciens acyl-CoA dehydrogenases |
Agrobacterium tumefaciens |
? |
- |
? |
1.5.5.1 | more |
the recombinant human enzyme is able to transfer electrons from the ETF protein from Agrobacterium tumefaciens strain C58 to 2,6-dichloroindophenol or coenzyme Q1 in an in vitro system |
Homo sapiens |
? |
- |
? |
1.5.5.1 | more |
although Agrobacterium tumefaciens ETF-mediated electron transfer to 2,6-DCIP is observed with a number of different dehydrogenases, the reduction of coenzyme Q1 through the DH/ETF/ETF-QO system is only observed with dimethylglycine dehydrogenase, but not with any of the tested Agrobacterium tumefaciens acyl-CoA dehydrogenases |
Agrobacterium tumefaciens C58 / ATCC 33970 |
? |
- |
? |