EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.14.73 | Brain Ischemia |
23041291 |
Cytochrome P450 2J2 is protective against global cerebral ischemia in transgenic mice. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
2
4
0 |
| 1.14.14.73 | Breast Neoplasms |
27720933 |
Activation of the pro-migratory bone morphogenetic protein receptor 1B gene in human MDA-MB-468 triple-negative breast cancer cells that over-express CYP2J2. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
1
0 |
| 1.14.14.73 | Breast Neoplasms |
28756208 |
Activation of ALDH1A1 in MDA-MB-468 breast cancer cells that over-express CYP2J2 protects against paclitaxel-dependent cell death mediated by reactive oxygen species. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
3
4
0 |
| 1.14.14.73 | Breast Neoplasms |
32354111 |
In-Depth Characterization of EpiIntestinal Microtissue as a Model for Intestinal Drug Absorption and Metabolism in Human. |
therapeutic application
unassigned |
2
0 |
| 1.14.14.73 | Breast Neoplasms |
32920985 |
Impact of gene polymorphisms in drug-metabolizing enzymes and transporters on trough concentrations of rivaroxaban in patients with atrial fibrillation. |
ongoing research
unassigned |
2
0 |
| 1.14.14.73 | Carcinogenesis |
30525564 |
A molecular design strategy to construct the near-infrared fluorescent probe for selectively sensing human cytochrome P450 2J2. |
diagnostic usage
therapeutic application
unassigned |
3
2
0 |
| 1.14.14.73 | Carcinoma |
15930289 |
Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 1.14.14.73 | Carcinoma |
17638876 |
Cytochrome p450 epoxygenase promotes human cancer metastasis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
4 |
| 1.14.14.73 | Carcinoma |
19550113 |
Expression of cytochrome P450 arachidonic acid epoxygenase 2J2 in human tumor tissues and cell lines. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 1.14.14.73 | Carcinoma |
21656078 |
The shunting of arachidonic acid metabolism to 5-lipoxygenase and cytochrome p450 epoxygenase antagonizes the anti-cancer effect of cyclooxygenase-2 inhibition in head and neck cancer cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
3
0 |
