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2.1.1.160: caffeine synthase

This is an abbreviated version!
For detailed information about caffeine synthase, go to the full flat file.

Word Map on EC 2.1.1.160

Reaction

S-adenosyl-L-methionine
+
1,7-dimethylxanthine
=
S-adenosyl-L-homocysteine
+
1,3,7-Trimethylxanthine

Synonyms

1-N-methyltransferase, 1NMT, 3, 7-dimethylxanthine methyltransferase, 3,7-dimethylxanthine methyltransferase, 7-N-methylxanthine methyltransferase, caffeine synthase, caffeine synthase 1, CCS, CCS1, coffee caffeine synthase 1, CS, CtCS6, DXMT, DXMT1, N-1 methyltransferase, TCS, TCS1, tea caffeine synthase, tea caffeine synthase 1, theobromine 1-N-methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.160 caffeine synthase

Application

Application on EC 2.1.1.160 - caffeine synthase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
agriculture
expression of the caffeine biosynthesis enzymes in transgenic crop plants may protect against the crop damaging larvae of pests
analysis
biotechnology
large-scale production of transgenic enzyme-deficient Coffea arabica and Camellia sinensis plants are a practical possibilty for production of decaffeinated coffee or tea
food industry
synthesis
production of caffeine in metabolically engineered Escherichia coli by the expression of caffeine synthase TCS1. Caffeine accumulation is increased using higher-level expression of the target enzymes, and enhancement of xanthine and S-adenosyl-L-methionine biosynthesis. The final strain produces up to 21.46 mg/l caffeine from 20 g/l of glucose in shake flask culture, yielding caffeine up to 2.96 mg/g glucose