2.1.1.292: carminomycin 4-O-methyltransferase

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For detailed information about carminomycin 4-O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.292

2.1.1.292

methyltransferases

sam-dependent

s-adenosyl-l-homocysteine

daunorubicin

peucetius

s-adenosyl-l-methionine-dependent

synthesis

Reaction

Synonyms

4-O-methyltransferase, anthracycline 4-O-methyltransferase, anthracycline methyltransferase, carminomycin 4-OMT, class I methyltransferase, COMT, DauK, DnrK

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.292 carminomycin 4-O-methyltransferase

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Results	in table
5	AA Sequence
1	Application
7	Cloned(Commentary)
4	Cofactor
2	Crystallization (Commentary)
10	General Information
3	Inhibitors
3	kcat/KM [mM/s]
6	KM Value [mM]
1	Metals/Ions
3	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
11	Organism
5	Pathway
57	PDB ID
3	pH Optimum
1	pH Range
6	Protein Variants
3	Purification (Commentary)
1	Reaction
11	Reference
2	Source Tissue
1	Specific Activity [micromol/min/mg]
24	Substrates and Products (Substrate)
3	Subunits
18	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Turnover Number [1/s]

KM Value

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KM Value on EC 2.1.1.292 - carminomycin 4-O-methyltransferase

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0.001

13-dihydrocarminomycin

Streptomyces sp.

pH 8.0, 37°C

722880

0.106

2-chloro-4-nitrophenol

Streptomyces peucetius

Q06528

pH 8.0, 37°C

755675

0.0005

carminomycin

Streptomyces sp.

pH 8.0, 37°C

722880

0.025 - 0.138

S-adenosyl-L-methionine

2 entries

0.335

S-adenosyl-[(3S)-3-amino-3-(1H-tetrazol-5-yl)propyl](methyl)sulfanium

Streptomyces peucetius

Q06528

pH 8.0, 37°C

755675