2.3.1.31: homoserine O-acetyltransferase
This is an abbreviated version!
For detailed information about homoserine O-acetyltransferase, go to the full flat file.
Word Map on EC 2.3.1.31
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2.3.1.31
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l-methionine
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ping-pong
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o-acetylhomoserine
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acetyl-enzyme
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succinyl-coa
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sulfhydrylase
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gamma-hydroxyl
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o-acetyl-l-homoserine
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medicine
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molecular biology
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drug development
- 2.3.1.31
- l-methionine
-
ping-pong
- o-acetylhomoserine
-
acetyl-enzyme
- succinyl-coa
-
sulfhydrylase
-
gamma-hydroxyl
- o-acetyl-l-homoserine
- medicine
- molecular biology
- drug development
Reaction
Synonyms
acetyltransferase, homoserine, CnHTA, DcsE, HAT, homoserine acetyltransferase, homoserine O-acetyltransferase, homoserine transacetylase, homoserine transsuccinylase, homoserine-O-transacetylase, HTA, HTS, L-homoserine O-acetyltransferase, MaHTA, MaMetX, MET2, MetA, MetX, MetXA, metX_1, metX_2, MhHTA, MhMetX, MsHAT, MtHTA, MtMetX, TmHTS
ECTree
2.3.1.31 homoserine O-acetyltransferaseAdvanced search results
results (
results (KM Value
KM Value on EC 2.3.1.31 - homoserine O-acetyltransferase
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.108
acetyl-CoA
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E237A, 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
0.143
acetyl-CoA
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E237Q, 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
0.158
acetyl-CoA
recombinant His-tagged enzyme, pH 8.0, 22°C
0.165
acetyl-CoA
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E250A, 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
0.174
acetyl-CoA
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E237D, 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
0.185
acetyl-CoA
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wild-type, 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
0.199
acetyl-CoA
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R249M , 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
0.249
acetyl-CoA
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S192A, 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
0.266
acetyl-CoA
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K163M, 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
1.35
acetyl-CoA
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K47R, 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
3.07
acetyl-CoA
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K47M, 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
0.06
L-homoserine
recombinant His-tagged enzyme, pH 8.0, 22°C
0.2
L-homoserine
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E111G, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM succinyl-CoA, 25°C
0.214
L-homoserine
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wild-type, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM acetyl-CoA, 25°C
0.287
L-homoserine
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E237Q, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM acetyl-CoA, 25°C
0.405
L-homoserine
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E237D, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM acetyl-CoA, 25°C
0.85
L-homoserine
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E237A, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM acetyl-CoA, 25°C
0.946
L-homoserine
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K47R, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM acetyl-CoA, 25°C
1
L-homoserine
recombinant His-tagged mutant P55G enzyme, pH 8.0, 30°C
1.02
L-homoserine
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S192A, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM acetyl-CoA, 25°C
1.38
L-homoserine
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K47M, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM acetyl-CoA, 25°C
2
L-homoserine
recombinant His-tagged mutant G52A/P55G enzyme, pH 8.0, 30°C
2.78
L-homoserine
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K163M, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM acetyl-CoA, 25°C
2.95
L-homoserine
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E250A, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM acetyl-CoA, 25°C
13.8
L-homoserine
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R249M, 50 mM potassium phosphate buffer, pH 7.5, 0.5 mM acetyl-CoA, 25°C
25
L-homoserine
recombinant His-tagged mutant G52A enzyme, pH 8.0, 30°C
98
L-homoserine
recombinant His-tagged wild-type enzyme, pH 8.0, 30°C
0.273
succinyl-CoA
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E111G, 50 mM potassium phosphate buffer, pH 7.5, 2 mM L-homoserine, 25°C
additional information
additional information
kinetic analysis
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additional information
additional information
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kinetic analysis
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additional information
additional information
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kcat/Km (substrate L-homoserine): 130000/Msec, (substrate acetyl-CoA): 878000/Msec
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