2.4.2.18: anthranilate phosphoribosyltransferase

This is an abbreviated version!
For detailed information about anthranilate phosphoribosyltransferase, go to the full flat file.

Reaction

Synonyms

AnPRT, anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase, anthranilate phosphoribosyl transferase, anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase, anthranilate phosphoribosyltransferase, anthranilate PRT, anthranilate-5-phosphoribosylphosphate phosphoribosyltransferase, anthranilate-PP-ribose-P phosphoribosyltransferase, More, Pat, phosphoribosyl-anthranilate pyrophosphorylase, phosphoribosylanthranilate pyrophosphorylase, phosphoribosylanthranilate transferase, phosphoribosyltransferase, anthranilate, PR transferase, PRT, sAnPRT, ssAnPRT, SSO0890, ssTrpD, strpD, Trp D, TrpD, TTC1491

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.18 anthranilate phosphoribosyltransferase

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Results	in table
1	Activating Compound
35125	AA Sequence
1	CAS Registry Number
20	Cloned(Commentary)
11	Crystallization (Commentary)
4	General Information
4	General Stability
23	Inhibitors
16	kcat/KM [mM/s]
2	Ki Value [mM]
82	KM Value [mM]
25	Metals/Ions
41	Molecular Weight [Da]
63	Natural Substrates/ Products (Substrates)
118	Organism
6	Pathway
150	PDB ID
7	pH Optimum
1	pI Value
46	Protein Variants
27	Purification (Commentary)
2	Reaction
2	Reaction Type
63	Reference
1	Renatured (Commentary)
1	Source Tissue
15	Specific Activity [micromol/min/mg]
4	Storage Stability
107	Substrates and Products (Substrate)
49	Subunits
89	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
22	Temperature Stability [°C]
78	Turnover Number [1/s]

General Stability

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General Stability on EC 2.4.2.18 - anthranilate phosphoribosyltransferase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

dilution inactivates

Klebsiella aerogenes

-

638674

freezing and thawing inactivates

Klebsiella aerogenes

-

638674

glycerol, 10%, is essential for storage, but it must be replaced by polyethylene glycol to achieve crystals that are not severely temperature dependent and radiation sensitive

Hafnia alvei

-

638676

the enzyme is either digested by trypsin, V8-protease or thermolysin after incubation for 1 h at 25°C but not by thermolysin at 70°C

Saccharolobus solfataricus

P50384

638678