2.5.1.48: cystathionine gamma-synthase
This is an abbreviated version!
For detailed information about cystathionine gamma-synthase, go to the full flat file.
Word Map on EC 2.5.1.48
-
2.5.1.48
-
homocystinuria
-
transsulfuration
-
beta-lyase
-
gamma-lyase
-
sulfhydrylase
-
o-acetylhomoserine
-
gamma-replacement
-
l-cystathionine
-
cystathionase
-
o-phosphohomoserine
-
paucicostata
-
gamma-elimination
-
homocystine
-
s-methylmethionine
-
remethylation
-
synthesis
- 2.5.1.48
- homocystinuria
-
transsulfuration
-
beta-lyase
-
gamma-lyase
-
sulfhydrylase
- o-acetylhomoserine
-
gamma-replacement
- l-cystathionine
- cystathionase
- o-phosphohomoserine
- paucicostata
-
gamma-elimination
- homocystine
- s-methylmethionine
-
remethylation
- synthesis
Reaction
Synonyms
AtCGS, CGS, CGS1, CS,26, cystathionine gamma-synthase, cystathionine synthase, cystathionine synthetase, cystathionine-gamma-synthase, EC 4.2.99.9, homoserine O-transsuccinylase, homoserine transsuccinylase, HTS, MetB, O-succinyl-L-homoserine succinate-lyase (adding cysteine), O-succinylhomoserine (Thiol)-lyase, O-succinylhomoserine synthase, O-succinylhomoserine synthetase, synthase, cystathionine gamma-
ECTree
2.5.1.48 cystathionine gamma-synthaseAdvanced search results
results (
results (Natural Substrates Products
Natural Substrates Products on EC 2.5.1.48 - cystathionine gamma-synthase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
O-succinyl-L-homoserine + L-selenocysteine
selenocystathionine + succinate
-
first step in conversion of selenocysteine to volatile dimethylselenide
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
-
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
constitutive overexpression of the enzyme in Arabidopsis leads to accumulation of soluble methionine and S-methylmethionine
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
key enzyme of Met biosynthesis
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
enzyme catalyzes the first step in methionine biosynthesis, overview
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
the second enzyme of the methionine biosynthetic pathway
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
key intermediate in transsulfuration pathways
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
first step in bacterial transsulfuration pathway
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
methionine biosynthesis
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
the enzyme catalyzes the first reaction specific for methionine biosynthesis
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
-
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
essential step in bacterial methionine biosynthesis
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
the expression of the enzyme is light-inducible
-
-
?
O-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
the enzyme catalyzes a near-equilibrium reaction and does not display features of a pathway-regulating enzyme
-
-
?
O4-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
-
-
-
?
O4-succinyl-L-homoserine + L-cysteine
L-cystathionine + succinate
-
-
-
-
?
additional information
?
-
S-adenosyl-L-methionine is an effector in the posttranscriptional autoregulation of the CGS1 gene
-
-
?
additional information
?
-
-
S-adenosyl-L-methionine is an effector in the posttranscriptional autoregulation of the CGS1 gene
-
-
?
additional information
?
-
-
the enzyme might by rate-limiting in selenium volatilization
-
-
?
