Reference on EC 2.7.7.9 - UTP-glucose-1-phosphate uridylyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kalckar, H.M.
The role of phosphoglycosyl compounds in the biosynthesis of nucleosides and nucleotides
Biochim. Biophys. Acta
12
250-264
1953
Saccharomyces cerevisiae, Saccharomyces fragilis
Lobelle-Rich, P.A.; Reeves, R.E.
Separation and characterization of two UTP-utilizing hexose phosphate uridylyltransferases from Entamoeba histolytica
Mol. Biochem. Parasitol.
7
173-182
1983
Entamoeba histolytica
Chacko, C.M.; McCrone, L.; Nadler, H.L.
Uridine diphosphoglucose pyrophosphorylase and uridine diphosphogalactose pyrophosphorylase in human skin fibroblasts derived from normal and galactosemic individuals
Biochim. Biophys. Acta
268
113-120
1972
Homo sapiens
Lee, L.J.; Kimura, A.; Tochikura, T.
Presence of a single enzyme catalyzing the pyrophosphorolysis of UDP-glucose and UDP-galactose in Bifidobacterium bifidum
Biochim. Biophys. Acta
527
301-304
1978
Bifidobacterium bifidum
Lee, L.J.; Kimura, A.; Tochikura, T.
Purification and properties of UDP-glucose (UDP-galactose) pyrophosphorylase from Bifidobacterium bifidum
J. Biochem.
86
923-928
1979
Bifidobacterium bifidum
Smart, E.L.; Pharr, D.M.
Separation and characteristics of galactose-1-phosphate and glucose-1-phosphate uridyltranferase from fruit peduncles of cucumber
Planta
153
370-375
1981
Cucumis sativus
Sowokinos, J.R.
Pyrophphosphorylases in Solanum tuberosum, II. Catalytic properties an reguation of ADP-glucose and UDP-glucose pyrophosphorylase activities in potatoes
Plant Physiol.
68
924-929
1981
Solanum tuberosum
Kimura, S.; Mitsui, T.; Matsuoka, T.; Igaue, I.
Purification, characterization and localization of rice UDP-glucose pyrophosphorylase
Plant Physiol. Biochem.
30
683-693
1992
Oryza sativa
-
Tovar, J.; Ruz-Herrera, J.
Purification and properties of glucose-1-phosphate uridylyltransferase from Neurospora crassa
Exp. Mycol.
11
36-48
1987
Neurospora crassa
-
Dutta, S.K.
UDPglucose pyrophosphorylase from Ehrlich ascites carcinoma cell--purification and characterization
Indian J. Biochem. Biophys.
22
203-207
1985
Mus musculus
Hondo, T.; Hara, A.; Funaguma, T.
The purification and some properties of the UDP-glucose pyrophosphorylase from pollen of Typha latifolia L.
Plant Cell Physiol.
24
61-69
1983
Typha latifolia
-
Sadurska, B.; Szymczyk, T.
Properties of UDPG pyrophosphorylase from rat salivary glands and liver
Arch. Oral Biol.
23
639-646
1978
Rattus norvegicus
Hopper, J.E.; Dickinson, D.B.
Partial purification and sugar nucleotide inhibition of UDP-glucose pyrophosphorylase from Lilium longiflorum pollen
Arch. Biochem. Biophys.
148
523-535
1972
Lilium longiflorum
Aksamit, R.R.; Ebner, K.E.
Purification, properties and kinetic analysis of UDP-glucose pyrophosphorylase from bovine mammary tissue
Biochim. Biophys. Acta
268
102-112
1972
Bos taurus
Hopper, J.E.; Dickinson, D.B.
Sugar nucleotide inhibition of UDP-glucose pyrophosphorylase from calf liver
Biochim. Biophys. Acta
309
307-317
1973
Bos taurus
Turnquist, R.L.; Turnquist, M.M.; Bachmann, R.C.; Hansen, R.G.
Uridine diphosphate glucose pyrophosphorylase: differential heat inactivation and further characterization of human liver enzyme
Biochim. Biophys. Acta
364
59-67
1974
Homo sapiens
Bergamini, C.; Signorini, M.; Ferrari, C.; Dallocchio, F.
Purification of muscle uridine diphosphoglucose pyrophosphorylase by hydrophobic chromatography
Anal. Biochem.
13
35-38
1984
Oryctolagus cuniculus
-
Azzar, G.; Persat, F.; Degiuli, A.; Got, R.
Purification of a UTP:D-glucose-1-phosphate uridylyltransferase from Golgi apparatus of cat liver by affinity chromatography on UTP-agarose
Anal. Biochem.
142
518-520
1984
Felis catus
Persat, F.; Azzar, G.; Martel, M.B.; Got, R.
Properties of uridine diphosphate glucose pyrophosphorylase from Golgi apparatus of liver
Biochim. Biophys. Acta
749
329-332
1983
Felis catus
Turnquist, R.L.; Gillett, T.A.; Hansen, R.G.
Uridine diphosphate glucose pyrophosphorylase. Crystallization and properties of the enzyme from rabbit liver and species comparisons
J. Biol. Chem.
249
7695-7700
1974
Bos taurus, Oryctolagus cuniculus, Homo sapiens
Weissborn, A.C.; Liu, Q.; Rumley, M.K.; Kennedy, E.P.
UTP: alpha-D-glucose-1-phosphate uridylyltransferase of Escherichia coli: isolation and DNA sequence of the galU gene and purification of the enzyme
J. Bacteriol.
176
2611-2618
1994
Escherichia coli
Elling, L.; Kula, M.R.
Purification of UDP-glucose pyrophosphorylase from germinated barley (malt)
J. Biotechnol.
34
157-163
1994
Hordeum vulgare subsp. vulgare
Nakano, K.; Omura, Y.; Tagaya, M.; Fukui, T.
UDP-glucose pyrophosphorylase from potato tuber: purification and characterization
J. Biochem.
106
528-532
1989
Solanum tuberosum
Sowokinos, J.R.; Spychalla, J.P.; Desborough, S.L.
Pyrophosphorylases in Solanum tuberosum. IV. Purification, tissue localization, and physicochemical properties of UDP-glucose pyrophosphorylase
Plant Physiol.
101
1073-1080
1993
Solanum tuberosum
Gustafson, G.L.; Gander, J.E.
Uridine diphosphate glucose pyrophosphorylase from Sorghum vulgare. Purification and kinetic properties
J. Biol. Chem.
247
1387-1397
1972
Sorghum bicolor
Katsube, T.; Kazuta, Y.; Mori, H.; Nakano, K.; Tanizawa, K.; Fukui, T.
UDP-glucose pyrophosphorylase from potato tuber: cDNA cloning and sequencing
J. Biochem.
108
321-326
1990
Solanum tuberosum
Rudick, V.L.; Weisman, R.A.
Uridine diphosphate glucose pyrophosphorylase of Acanthamoeba castellanii. Purification, kinetic, and developmental studies
J. Biol. Chem.
249
7832-7840
1974
Acanthamoeba castellanii, Acanthamoeba castellanii NEFF
Nakae, T.; Nikaido, H.
Multiple molecular forms of uridine diphosphate glucose pyrophosphorylase from Salmonella typhimurium. I. Catalytic properties of various forms
J. Biol. Chem.
246
4386-4396
1971
Salmonella enterica subsp. enterica serovar Typhimurium
Dimond, R.L.; Farnsworth, P.A.; Loomis, W.F.
Isolation and characterization of mutations affecting UDPG pyrophosphorylase activity in Dictyostelium discoideum
Dev. Biol.
50
169-181
1976
Dictyostelium discoideum
Turnquist, R.L.; Hansen, R.G.
Uridine diphosphoryl glucose pyrophosphorylase
The Enzymes, 3rd. Ed. (Boyer, P. D. , ed. )
8
51-71
1973
Acetabularia sp., Beta vulgaris subsp. vulgaris, Bombyx mori, Bos taurus, Saccharomyces cerevisiae, Canis lupus familiaris, Capra hircus, Gallus gallus, Columba sp., Oryctolagus cuniculus, Dictyostelium discoideum, Escherichia coli, Ovis aries, Homo sapiens, Pisum sativum, Rattus norvegicus, Salmonella enterica subsp. enterica serovar Typhimurium, Zea mays
-
Daran, J.M.; Dallies, N.; Thines-Sempoux, D.; Paquet, V.; Francois, J.
Genetic and biochemical characterization of the UGP1 gene encoding the UDP-glucose pyrophosphorylase from Saccharomyces cerevisiae
Eur. J. Biochem.
233
520-530
1995
Saccharomyces cerevisiae
Lightcap, E.S.; Frey, P.A.
m-Monothiopyrophosphate as a substrate for inorganic pyrophosphatase and UDP-glucose pyrophosphorylase
Arch. Biochem. Biophys.
335
183-190
1996
Saccharomyces cerevisiae
Chang, H.Y.; Peng, H.L.; Chao, Y.C.; Duggleby, R.G.
The importance of conserved residues in human liver UDPglucose pyrophosphorylase
Eur. J. Biochem.
236
723-728
1996
Homo sapiens
Elling, L.
Kinetic characterization of UDP-glucose pyrophosphorylase from germinated barley (malt)
Phytochemistry
42
955-960
1996
Hordeum vulgare subsp. vulgare
-
Eimert, K.; Villand, P.; Kilian, A.; Kleczkowski, L.A.
Cloning and characterization of several cDNAs for UDP-glucose pyrophosphorylase from barley (Hordeum vulgare) tissues
Gene
170
227-232
1996
Hordeum vulgare (Q43772), Hordeum vulgare
Degeest, B.; De Vuyst, L.
Correlation of activities of the enzymes a-phosphoglucomutase, UDP-galactose 4-epimerase, and UDP-glucose pyrophosphorylase with exopolysaccharide biosynthesis by Streptococcus thermophilus LY03
Appl. Environ. Microbiol.
66
3519-3527
2000
Streptomyces thermophilus, Streptomyces thermophilus LY03
Ciereszko, I.; Johansson, H.; Kleczkowski, L.A.
Sucrose and light regulation of a cold-inducible UDP-glucose pyrophosphorylase gene via a hexokinase-independent and abscisic acid-insensitive pathway in Arabidopsis
Biochem. J.
354
67-72
2001
Arabidopsis thaliana
Magee, C.; Nurminskaya, M.; Linsenmayer, T.F.
UDP-glucose pyrophosphorylase: up-regulation in hypertrophic cartilage and role in hyaluronan synthesis
Biochem. J.
360
667-674
2001
Gallus gallus
Martz, F.; Wilczynska, M.; Kleczkowski, L.A.
Oligomerization status, with the monomer as active species, defines catalytic efficiency of UDP-glucose pyrophosphorylase
Biochem. J.
367
295-300
2002
Hordeum vulgare (Q43772), Hordeum vulgare
Kim, H.; Wu, C.A.; Kim, D.Y.; Han, Y.H.; Ha, S.C.; Kim, C.S.; Suh, S.W.; Kim, K.K.
Crystallization and preliminary X-ray crystallographic study of UDP-glucose pyrophosphorylase (UGPase) from Helicobacter pylori
ACTA CRYSTALLOGR. SECT. D
60
1447-1449
2004
Helicobacter pylori, Helicobacter pylori 26 695
Silva, E.; Marques, A.R.; Fialho, A.M.; Granja, A.T.; Sa-Correia, I.
Proteins encoded by Sphingomonas elodea ATCC 31461 rmlA and ugpG genes, involved in gellan gum biosynthesis, exhibit both dTDP- and UDP-glucose pyrophosphorylase activities
Appl. Environ. Microbiol.
71
4703-4712
2005
Sphingomonas elodea
Bonofiglio, L.; Garcia, E.; Mollerach, M.
Biochemical characterization of the pneumococcal glucose 1-phosphate uridylyltransferase (GalU) essential for capsule biosynthesis
Curr. Microbiol.
51
217-221
2005
Streptococcus pneumoniae
Guranowski, A.; de Diego, A.; Sillero, A.; Gunther Sillero, M.A.
Uridine 5'-polyphosphates (p4U and p5U) and uridine(5')polyphospho(5')nucleosides (Up(n)Ns) can be synthesized by UTP:glucose-1-phosphate uridylyltransferase from Saccharomyces cerevisiae
FEBS Lett.
561
83-88
2004
Saccharomyces cerevisiae
Reynolds, T.H.t.; Pak, Y.; Harris, T.E.; Manchester, J.; Barrett, E.J.; Lawrence, J.C., Jr.
Effects of insulin and transgenic overexpression of UDP-glucose pyrophosphorylase on UDP-glucose and glycogen accumulation in skeletal muscle fibers
J. Biol. Chem.
280
5510-5515
2005
Mus musculus
Zhang, Z.; Tsujimura, M.; Akutsu, J.; Sasaki, M.; Tajima, H.; Kawarabayasi, Y.
Identification of an extremely thermostable enzyme with dual sugar-1-phosphate nucleotidylyltransferase activities from an acidothermophilic archaeon, Sulfolobus tokodaii strain 7
J. Biol. Chem.
280
9698-9705
2005
Sulfurisphaera tokodaii (Q975F9), Sulfurisphaera tokodaii 7 (Q975F9)
Ciereszko, I.; Johansson, H.; Kleczkowski, L.A.
Interactive effects of phosphate deficiency, sucrose and light/dark conditions on gene expression of UDP-glucose pyrophosphorylase in Arabidopsis
J. Plant Physiol.
162
343-353
2005
Arabidopsis thaliana
Kleczkowski, L.A.; Martz, F.; Wilczynska, M.
Factors affecting oligomerization status of UDP-glucose pyrophosphorylase
Phytochemistry
66
2815-2821
2005
Hordeum vulgare (Q43772), Hordeum vulgare
Chang, H.Y.; Huang, H.C.; Lee, J.H.; Peng, H.L.
Characterization of a putative Pseudomonas UDPglucose pyrophosphorylase
Proc. Natl. Sci. Counc. Repub. China Part B Life Sci.
23
74-84
1999
Pseudomonas aeruginosa
Hedegaard, J.; Horn, P.; Lametsch, R.; Sondergaard Moller, H.; Roepstorff, P.; Bendixen, C.; Bendixen, E.
UDP-glucose pyrophosphorylase is upregulated in carriers of the porcine RN- mutation in the AMP-activated protein kinase
Proteomics
4
2448-2454
2004
Sus scrofa
Aragao, D.; Marques, A.R.; Frazao, C.; Enguita, F.J.; Carrondo, M.A.; Fialho, A.M.; Sa-Correia, I.; Mitchell, E.P.
Cloning, expression, purification, crystallization and preliminary structure determination of glucose-1-phosphate uridylyltransferase (UgpG) from Sphingomonas elodea ATCC 31461 bound to glucose-1-phosphate
Acta Crystallogr. Sect. F
F62
930-934
2006
Sphingomonas elodea
Meng, M.; Geisler, M.; Johansson, H.; Mellerowicz, E.J.; Karpinski, S.; Kleczkowski, L.A.
Differential tissue/organ-dependent expression of two sucrose- and cold-responsive genes for UDP-glucose pyrophosphorylase in Populus
Gene
389
186-195
2007
Populus tremula x Populus tremuloides
Aragao, D.; Fialho, A.M.; Marques, A.R.; Mitchell, E.P.; Sa-Correia, I.; Frazao, C.
The complex of Sphingomonas elodea ATCC 31461 glucose-1-phosphate uridylyltransferase with glucose-1-phosphate reveals a novel quaternary structure, unique among nucleoside diphosphate-sugar pyrophosphorylase members
J. Bacteriol.
189
4520-4528
2007
Sphingomonas elodea
Lamerz, A.C.; Haselhorst, T.; Bergfeld, A.K.; von Itzstein, M.; Gerardy-Schahn, R.
Molecular cloning of the Leishmania major UDP-glucose pyrophosphorylase, functional characterization, and ligand binding analyses using NMR spectroscopy
J. Biol. Chem.
281
16314-16322
2006
Leishmania major (Q4QDU3), Leishmania major
Steiner, T.; Lamerz, A.C.; Hess, P.; Breithaupt, C.; Krapp, S.; Bourenkov, G.; Huber, R.; Gerardy-Schahn, R.; Jacob, U.
Open and closed structures of the UDP-glucose pyrophosphorylase from Leishmania major
J. Biol. Chem.
282
13003-13010
2007
Leishmania major
Seo, M.; Im, E.; Singh, D.; Rajkarnikar, A.; Kwon, H.; Hyun, C.; Suh, J.; Pyun, Y.; Kim, S.
Characterization of D-glucose alpha -1-phosphate uridylyltransferase (VldB) and glucokinase (VldC) involved in validamycin biosynthesis of Streptomyces hygroscopicus var. limoneus KCCM 11405
J. Microbiol. Biotechnol.
16
1311-1315
2006
Streptomyces hygroscopicus, Streptomyces hygroscopicus KCCM 11405
-
Roeben, A.; Plitzko, J.M.; Koerner, R.; Boettcher, U.M.; Siegers, K.; Hayer-Hartl, M.; Bracher, A.
Structural basis for subunit assembly in UDP-glucose pyrophosphorylase from Saccharomyces cerevisiae
J. Mol. Biol.
364
551-560
2006
Saccharomyces cerevisiae
McCoy, J.G.; Bitto, E.; Bingman, C.A.; Wesenberg, G.E.; Bannen, R.M.; Kondrashov, D.A.; Phillips, G.N.
Structure and dynamics of UDP-glucose pyrophosphorylase from Arabidopsis thaliana with bound UDP-glucose and UTP
J. Mol. Biol.
366
830-841
2007
Arabidopsis thaliana (Q9M9P3), Arabidopsis thaliana
Vilches, S.; Canals, R.; Wilhelms, M.; Salo, M.T.; Knirel, Y.A.; Vinogradov, E.; Merino, S.; Tomas, J.M.
Mesophilic Aeromonas UDP-glucose pyrophosphorylase (GalU) mutants show two types of lipopolysaccharide structures and reduced virulence
Microbiology
153
2393-2404
2007
Aeromonas hydrophila
Chen, R.; Zhao, X.; Shao, Z.; Zhu, L.; He, G.
Multiple isoforms of UDP-glucose pyrophosphorylase in rice
Physiol. Plant.
129
725-736
2007
Oryza sativa (A3QQQ3)
Coleman, H.D.; Ellis, D.D.; Gilbert, M.; Mansfield, S.D.
Up-regulation of sucrose synthase and UDP-glucose pyrophosphorylase impacts plant growth and metabolism
Plant Biotechnol. J.
4
87-101
2006
Nicotiana tabacum
Chen, R.; Zhao, X.; Shao, Z.; Wei, Z.; Wang, Y.; Zhu, L.; Zhao, J.; Sun, M.; He, R.; He, G.
Rice UDP-glucose pyrophosphorylase1 is essential for pollen callose deposition and its cosuppression results in a new type of thermosensitive genic male sterility
Plant Cell
19
847-861
2007
Oryza sativa (A3QQQ3), Oryza sativa
Dai, N.; Petreikov, M.; Portnoy, V.; Katzir, N.; Pharr, D.M.; Schaffer, A.A.
Cloning and expression analysis of a UDP-galactose/glucose pyrophosphorylase from melon fruit provides evidence for the major metabolic pathway of galactose metabolism in raffinose oligosaccharide metabolizing plants
Plant Physiol.
142
294-304
2006
Cucumis melo (Q19TV8)
Thoden, J.B.; Holden, H.M.
Active site geometry of glucose-1-phosphate uridylyltransferase
Protein Sci.
16
1379-1388
2007
Corynebacterium glutamicum
Thoden, J.B.; Holden, H.M.
The molecular architecture of glucose-1-phosphate uridylyltransferase
Protein Sci.
16
432-440
2007
Escherichia coli (P0AEP3), Escherichia coli
Conti, A.; Giuffrida, M.G.; Hoffmann-Sommergruber, K.; Wagner, S.; Amato, S.; Mistrello, G.; Asero, R.
Identification of latex UDP glucose pyrophosphorylase (Hev b UDPGP) as a novel cause of latex fruit allergy syndrome
Eur. Ann. Allergy Clin. Immunol.
39
116-118
2007
Hevea brasiliensis
Siddique, S.; Endres, S.; Atkins, J.M.; Szakasits, D.; Wieczorek, K.; Hofmann, J.; Blaukopf, C.; Urwin, P.E.; Tenhaken, R.; Grundler, F.M.; Kreil, D.P.; Bohlmann, H.
Myo-inositol oxygenase genes are involved in the development of syncytia induced by Heterodera schachtii in Arabidopsis roots
New Phytol.
184
457-472
2009
Arabidopsis thaliana (P57751), Arabidopsis thaliana (Q9M9P3)
Prasad, S.B.; Jayaraman, G.; Ramachandran, K.B.
Hyaluronic acid production is enhanced by the additional co-expression of UDP-glucose pyrophosphorylase in Lactococcus lactis
Appl. Microbiol. Biotechnol.
86
273-283
2010
Streptococcus equi subsp. zooepidemicus (Q8GQP9), Streptococcus equi subsp. zooepidemicus
Meng, M.; Wilczynska, M.; Kleczkowski, L.A.
Molecular and kinetic characterization of two UDP-glucose pyrophosphorylases, products of distinct genes, from Arabidopsis
Biochim. Biophys. Acta
1784
967-972
2008
Arabidopsis thaliana (P57751), Arabidopsis thaliana (Q9M9P3)
Meng, M.; Fitzek, E.; Gajowniczek, A.; Wilczynska, M.; Kleczkowski, L.A.
Domain-specific determinants of catalysis/substrate binding and the oligomerization status of barley UDP-glucose pyrophosphorylase
Biochim. Biophys. Acta
1794
1734-1742
2009
Hordeum vulgare (Q43772), Hordeum vulgare
Bosco, M.B.; Machtey, M.; Iglesias, A.A.; Aleanzi, M.
UDPglucose pyrophosphorylase from Xanthomonas spp. Characterization of the enzyme kinetics, structure and inactivation related to oligomeric dissociation
Biochimie
91
204-213
2009
Xanthomonas campestris pv. campestris (A0A0H2X8N4), Xanthomonas citri (Q8PK83)
Gupta, S.; Sowokinos, J.; Hahn, I.
Regulation of UDP-glucose pyrophosphorylase isozyme UGP5 associated with cold-sweetening resistance in potatoes
J. Plant Physiol.
165
679-690
2008
Solanum tuberosum
Meng, M.; Geisler, M.; Johansson, H.; Harholt, J.; Scheller, H.V.; Mellerowicz, E.J.; Kleczkowski, L.A.
UDP-glucose pyrophosphorylase is not rate limiting, but is essential in Arabidopsis
Plant Cell Physiol.
50
998-1011
2009
Arabidopsis thaliana (P57751), Arabidopsis thaliana (Q94B70)
Okazaki, Y.; Shimojima, M.; Sawada, Y.; Toyooka, K.; Narisawa, T.; Mochida, K.; Tanaka, H.; Matsuda, F.; Hirai, A.; Hirai, M.Y.; Ohta, H.; Saito, K.
A chloroplastic UDP-glucose pyrophosphorylase from Arabidopsis is the committed enzyme for the first step of sulfolipid biosynthesis
Plant Cell
21
892-909
2009
Arabidopsis thaliana (Q94B70), Arabidopsis thaliana
Lai, X.; Wu, J.; Chen, S.; Zhang, X.; Wang, H.
Expression, purification, and characterization of a functionally active Mycobacterium tuberculosis UDP-glucose pyrophosphorylase
Protein Expr. Purif.
61
50-56
2008
Mycobacterium tuberculosis (O05576), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (O05576)
Yu, Q.; Zheng, X.
The crystal structure of human UDP-glucose pyrophosphorylase reveals a latch effect that influences enzymatic activity
Biochem. J.
442
283-291
2012
Drosophila melanogaster (A5XCL5), Danio rerio (B8JMZ1), Saccharomyces cerevisiae (C7GP37), Homo sapiens (Q16851), Homo sapiens, Caenorhabditis elegans (Q9XUS5)
Guenther Sillero, M.A.; de Diego, A.; Sillero, A.
Methylenebisphosphonate and triphosphate derivatives of the mevalonate pathway are substrates of yeast UTP:glucose-1-phosphate uridylyltransferase
Biochimie
94
1871-1875
2012
Saccharomyces cerevisiae
Pan, S.; Yao, D.; Chen, J.; Wu, S.
Influence of controlled pH on the activity of UDPG-pyrophosphorylase in Aureobasidium pullulans
Carbohydr. Polym.
92
629-632
2013
Aureobasidium pullulans, Aureobasidium pullulans CJ001
Marino, K.; Guether, M.L.; Wernimont, A.K.; Amani, M.; Hui, R.; Ferguson, M.A.
Identification, subcellular localization, biochemical properties, and high-resolution crystal structure of Trypanosoma brucei UDP-glucose pyrophosphorylase
Glycobiology
20
1619-1630
2010
Trypanosoma brucei (D3HTY9), Trypanosoma brucei, Trypanosoma brucei 427 (D3HTY9)
Fuehring, J.; Damerow, S.; Fedorov, R.; Schneider, J.; Muenster-Kuehnel, A.K.; Gerardy-Schahn, R.
Octamerization is essential for enzymatic function of human UDP-glucose pyrophosphorylase
Glycobiology
23
426-437
2013
Homo sapiens
Chivasa, S.; Tome, D.F.; Slabas, A.R.
UDP-glucose pyrophosphorylase is a novel plant cell death regulator
J. Proteome Res.
12
1743-1753
2013
Arabidopsis thaliana, Arabidopsis thaliana Col-0
Ma, Z.; Fan, H.J.; Lu, C.P.
Molecular cloning and analysis of the UDP-glucose pyrophosphorylase in Streptococcus equi subsp. zooepidemicus
Mol. Biol. Rep.
38
2751-2760
2011
Streptococcus equi (Q8GQP8), Streptococcus equi
Huang, Z.; Gan, Z.; He, Y.; Li, Y.; Liu, X.; Mu, H.
Functional analysis of a rice late pollen-abundant UDP-glucose pyrophosphorylase (OsUgp2) promoter
Mol. Biol. Rep.
38
4291-4302
2011
Oryza sativa (Q9M4X0), Oryza sativa
Kim, H.; Choi, J.; Kim, T.; Lokanath, N.K.; Ha, S.C.; Suh, S.W.; Hwang, H.Y.; Kim, K.K.
Structural basis for the reaction mechanism of UDP-glucose pyrophosphorylase
Mol. Cells
29
397-405
2010
Helicobacter pylori (O25363), Helicobacter pylori
Decker, D.; Meng, M.; Gornicka, A.; Hofer, A.; Wilczynska, M.; Kleczkowski, L.A.
Substrate kinetics and substrate effects on the quaternary structure of barley UDP-glucose pyrophosphorylase
Phytochemistry
79
39-45
2012
Hordeum vulgare
Shimojima, M.
Biosynthesis and functions of the plant sulfolipid
Prog. Lipid Res.
50
234-239
2011
Arabidopsis thaliana, Spinacia oleracea
Zhang, Z.; Shimizu, Y.; Kawarabayasi, Y.
Characterization of the amino acid residues mediating the unique amino-sugar-1-phosphate acetyltransferase activity of the archaeal ST0452 protein
Extremophiles
19
417-427
2015
Sulfurisphaera tokodaii (Q975F9), Sulfurisphaera tokodaii 7 (Q975F9)
Baron, D.; Bravo, J.; Maia, I.; Pina, A.; Ferreira, G.
UGP gene expression and UDP-glucose pyrophosphorylase enzymatic activity in grafting annonaceous plants
Acta Physiol. Plant.
38
79
2016
Annona emarginata, Annona cherimola (C0L7E5)
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De Bruyn, F.; Beauprez, J.; Maertens, J.; Soetaert, W.; De Mey, M.
Unraveling the Leloir pathway of Bifidobacterium bifidum: significance of the uridylyltransferases
Appl. Environ. Microbiol.
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Bifidobacterium bifidum (M4M6L5), Bifidobacterium bifidum PRL2010 (M4M6L5)
Yi, D.; Huh, W.
UDP-glucose pyrophosphorylase Ugp1 is involved in oxidative stress response and long-term survival during stationary phase in Saccharomyces cerevisiae
Biochem. Biophys. Res. Commun.
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Saccharomyces cerevisiae (P32861)
Ebrecht, A.C.; Asencion Diez, M.D.; Piattoni, C.V.; Guerrero, S.A.; Iglesias, A.A.
The UDP-glucose pyrophosphorylase from Giardia lamblia is redox regulated and exhibits promiscuity to use galactose-1-phosphate
Biochim. Biophys. Acta
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Giardia intestinalis (A8BJJ7), Giardia intestinalis, Giardia intestinalis ATCC 50803 (A8BJJ7)
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Cloning cDNA and functional characterization of UDP-glucose pyrophosphorylase in Dendrobium officinale
Biol. Plant.
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Dendrobium catenatum (A0A068BLC7)
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Yi, D.G.; Huh, W.K.
PKA, PHO and stress response pathways regulate the expression of UDP-glucose pyrophosphorylase through Msn2/4 in budding yeast
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Saccharomyces cerevisiae (P32861), Saccharomyces cerevisiae
Li, M.; Chen, T.; Gao, T.; Miao, Z.; Jiang, A.; Shi, L.; Ren, A.; Zhao, M.
UDP-glucose pyrophosphorylase influences polysaccharide synthesis, cell wall components, and hyphal branching in Ganoderma lucidum via regulation of the balance between glucose-1-phosphate and UDP-glucose
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Ganoderma lucidum
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Molecular cloning, characterization, and comparison of UDP-glucose pyrophosphorylase from Gracilaria chouae and Saccharina japonica
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Saccharina japonica (A0A0S3WYP3), Gracilaria chouae (A0A0S3X5N5)
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CugP is a novel ubiquitous non-GalU-type bacterial UDP-glucose pyrophosphorylase found in cyanobacteria
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Synechocystis sp. (P74285), Synechocystis sp.
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Identification and characterization of UDP-glucose pyrophosphorylase in cyanobacteria Anabaena sp. PCC 7120
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Nostoc sp. (Q8YS18), Nostoc sp. PCC 7120 (Q8YS18)
Medeot, D.B.; Romina Rivero, M.; Cendoya, E.; Contreras-Moreira, B.; Rossi, F.A.; Fischer, S.E.; Becker, A.; Jofre, E.
Sinorhizobium meliloti low molecular mass phosphotyrosine phosphatase SMc02309 modifies activity of the UDP-glucose pyrophosphorylase ExoN involved in succinoglycan biosynthesis
Microbiology
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Sinorhizobium meliloti, Sinorhizobium meliloti 2011
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Overexpression of UDP-glucose pyrophosphorylase from Larix gmelinii enhances vegetative growth in transgenic Arabidopsis thaliana
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Larix gmelinii (A0A068PCB8), Larix gmelinii
Fuehring, J.I.; Cramer, J.T.; Schneider, J.; Baruch, P.; Gerardy-Schahn, R.; Fedorov, R.
A quaternary mechanism enables the complex biological functions of octameric human UDP-glucose pyrophosphorylase, a key enzyme in cell metabolism
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Homo sapiens (Q16851), Homo sapiens
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Increasing the thermostable sugar-1-phosphate nucleotidylyltransferase activities of the archaeal ST0452 protein through site saturation mutagenesis of the 97th amino acid position
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Sulfurisphaera tokodaii (Q975F9), Sulfurisphaera tokodaii, Sulfurisphaera tokodaii DSM 16993 (Q975F9)
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Identification of a dTDP-rhamnose biosynthetic pathway that oscillates with the molting cycle in Caenorhabditis elegans
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Increasing the thermostable sugar-1-phosphate nucleotidylyltransferase activities of the archaeal ST0452 protein through site saturation mutagenesis of the 97th amino acid position
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Sulfurisphaera tokodaii (Q975F9), Sulfurisphaera tokodaii, Sulfurisphaera tokodaii DSM 16993 (Q975F9)
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Characterization of the biosynthetic pathway of nucleotide sugar precursor UDP-glucose during sphingan WL gum production in Sphingomonas sp. WG
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Elucidating paramylon and other carbohydrate metabolism in Euglena gracilis Kinetic characterization, structure and cellular localization of UDP-glucose pyrophosphorylase
Biochimie
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Euglena gracilis, Euglena gracilis UTEX 753
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Targeting Streptococcus pneumoniae UDP-glucose pyrophosphorylase (UGPase) in vitro validation of a putative inhibitor
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Identification of two highly promiscuous thermostable sugar nucleotidylyltransferases for glycorandomization
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Pyrococcus horikoshii
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Immobilization of the highly active UDP-glucose pyrophosphorylase from Thermocrispum agreste provides a highly efficient biocatalyst for the production of UDP-glucose
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Thermocrispum agreste (A0A2W4LV58), Thermocrispum agreste, Thermocrispum agreste DSM 44070 (A0A2W4LV58), Thermocrispum agreste DSM 44070
Deng, S.; Yao, C.; Zhang, X.; Jia, Z.; Shan, C.; Luo, X.; Lin, L.
Involvement of UDP-glucose pyrophosphorylase from Verticillium dahliae in cell morphogenesis, stress responses, and host infection
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Verticillium dahliae, Verticillium dahliae V07DF2
Zan, X.Y.; Wu, X.H.; Cui, F.J.; Zhu, H.A.; Sun, W.J.; Jiang, L.H.; Tao, T.L.; Zhao, X.
UDP-glucose pyrophosphorylase gene affects mycelia growth and polysaccharide synthesis of Grifola frondosa
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Grifola frondosa (MN788154), Grifola frondosa, Grifola frondosa CGMCC 5.626 (MN788154)
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Screening assay for inhibitors of a recombinant Streptococcus pneumoniae UDP-glucose pyrophosphorylase
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Streptococcus pneumoniae (Q54800), Streptococcus pneumoniae
Decker, D.; Oeberg, C.; Kleczkowski, L.A.
Identification and characterization of inhibitors of UDP-glucose and UDP-sugar pyrophosphorylases for in vivo studies
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Arabidopsis thaliana (P57751), Arabidopsis thaliana (Q9M9P3), Hordeum vulgare (Q43772)
Decker, D.; berg, C.; Kleczkowski, L.
The structure-activity relationship of the salicylimide derived inhibitors of UDP-sugar producing pyrophosphorylases
Plant Signal. Behav.
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Arabidopsis thaliana (Q9M9P3)
Cotrim, C.A.; Soares, J.S.M.; Kobe, B.; Menossi, M.
Crystal structure and insights into the oligomeric state of UDP-glucose pyrophosphorylase from sugarcane
PLoS ONE
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Saccharum hybrid cultivar SP80-3280 (A0A075E2Q1)
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