1.14.11.51: DNA N6-methyladenine demethylase

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For detailed information about DNA N6-methyladenine demethylase, go to the full flat file.

Word Map on EC 1.14.11.51

Reaction

N6-methyladenine in DNA
+
2-oxoglutarate
+
O2
=
adenine in DNA
+
formaldehyde
+
succinate
+
CO2

Synonyms

6mA DNA demethylase, ALKBH1, DMAD, DNA 6mA demethylase, NMAD-1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.51 DNA N6-methyladenine demethylase

Disease

Disease on EC 1.14.11.51 - DNA N6-methyladenine demethylase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Carcinogenesis
ALKBH1 Promotes N6-methyladenine DNA Modifications in Glioblastoma.
N6-Methyladenine DNA Modification in the Human Genome.
Carcinoma
N6-Hydroxymethyladenine: a hydroxylation derivative of N6-methyladenine in genomic DNA of mammals.
Glioblastoma
ALKBH1 Promotes N6-methyladenine DNA Modifications in Glioblastoma.
N6-methyladenine DNA Modification in Glioblastoma.
Neoplasm Metastasis
Expression of Demethylase Genes, FTO and ALKBH1, Is Associated with Prognosis of Gastric Cancer.
Neoplasms
Expression of Demethylase Genes, FTO and ALKBH1, Is Associated with Prognosis of Gastric Cancer.
N6-methyladenine DNA Modification in Glioblastoma.
N6-Methyladenine DNA Modification in the Human Genome.
Stomach Neoplasms
Expression of Demethylase Genes, FTO and ALKBH1, Is Associated with Prognosis of Gastric Cancer.