Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.11.7: procollagen-proline 3-dioxygenase

This is an abbreviated version!
For detailed information about procollagen-proline 3-dioxygenase, go to the full flat file.

Word Map on EC 1.14.11.7

Reaction

[procollagen]-L-proline
+
2-oxoglutarate
+
O2
=
[procollagen]-trans-3-hydroxy-L-proline
+
succinate
+
CO2

Synonyms

LEPRE1, Leprel1, Leprel2, More, oxygenase, protocollagen proline 3-di-, P3H1, P3H2, P3H3, PHD3, proline,2-oxoglutarate 3-dioxygenase, prolyl 3-hydroxylase, prolyl 3-hydroxylase 1, prolyl 3-hydroxylase 2, prolyl 3-hydroxylase-2, prolyl hydroxylase, prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating, protocollagen proline 3-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.7 procollagen-proline 3-dioxygenase

Cloned

Cloned on EC 1.14.11.7 - procollagen-proline 3-dioxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
DNA and amino acid sequence determination and analysis of wild-type and mutant enzymes
-
ectopic expression of P3H2 in cells with silenced endogenous genes
ectopic expression of P3H3 in cells with silenced endogenous genes
expression of both isoforms P3H1, P3H2 in Sf9 cell
gene LEPRE1 or P3h1