1.14.13.84: 4-hydroxyacetophenone monooxygenase

This is an abbreviated version!
For detailed information about 4-hydroxyacetophenone monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.84

Reaction

(4-hydroxyphenyl)ethan-1-one
+
NADPH
+
H+
+
O2
=
4-hydroxyphenyl acetate
+
NADP+
+
H2O

Synonyms

4-hydroxyacetophenone monooxygenase, arylketone monooxygenase, Baeyer-Villiger monooxygenase, hAPA, HAPMO, More, oxygenase, 4-hydroxyacetophenone mono-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.84 4-hydroxyacetophenone monooxygenase

Reference

Reference on EC 1.14.13.84 - 4-hydroxyacetophenone monooxygenase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kamerbeek, N.M.; Moonen, M.J.; van der Ven, J.G.; van Berkel, W.J.H.; Fraaije, M.W.; Janssen, D.B.
4- Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB: a novel flavoprotein catalyzing Baeyer-Villiger oxidation of aromatic compounds
Eur. J. Biochem.
268
2547-2557
2001
Pseudomonas fluorescens, Pseudomonas fluorescens (Q93TJ5), Pseudomonas fluorescens ACB, Pseudomonas fluorescens ACB (Q93TJ5)
Manually annotated by BRENDA team
Kamerbeek, N.M.; Olsthoorn, A.J.J.; Fraaije, M.W.; Janssen, D.B.
Substrate specificity and enantioselectivity of 4-hydroxyacetophenone monooxygenase
Appl. Environ. Microbiol.
69
419-426
2003
Pseudomonas fluorescens, Pseudomonas fluorescens ACB
Manually annotated by BRENDA team
Kamerbeek, N.M.; Fraaije, M.W.; Janssen, D.B.
Identifying determinants of NADPH specificity in Baeyer-Villiger monooxygenases
Eur. J. Biochem.
271
2107-2116
2004
Pseudomonas fluorescens, Pseudomonas fluorescens ACB
Manually annotated by BRENDA team
Tanner, A.; Hopper, D.J.
Conversion of 4-hydroxyacetophenone into 4-phenyl acetate by a flavin adenine dinucleotide-containing Baeyer-Villiger-type monooxygenase
J. Bacteriol.
182
6565-6569
2000
Pseudomonas putida, Pseudomonas putida JD1
Manually annotated by BRENDA team
Mihovilovic, M.D.; Kapitan, P.; Rydz, J.; Rudroff, F.; Ogink, F.H.; Fraaije, M.W.
Biooxidation of ketones with a cyclobutanone structural motif by recombinant whole-cells expressing 4-hydroxyacetophenone monooxygenase
J. Mol. Catal. B
32
135-140
2005
Pseudomonas fluorescens, Pseudomonas fluorescens ACB
-
Manually annotated by BRENDA team
van den Heuvel, R.H.; Tahallah, N.; Kamerbeek, N.M.; Fraaije, M.W.; van Berkel, W.J.; Janssen, D.B.; Heck, A.J.
Coenzyme binding during catalysis is beneficial for the stability of 4-hydroxyacetophenone monooxygenase
J. Biol. Chem.
280
32115-32121
2005
Pseudomonas fluorescens, Pseudomonas fluorescens ACB
Manually annotated by BRENDA team
de Gonzalo, G.; Torres Pazmino, D.E.; Ottolina, G.; Fraaije, M.W.; Carrea, G.
4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB as an oxidative biocatalyst in the synthesis of optically active sulfoxides
Tetrahedron Asymmetry
17
130-135
2006
Pseudomonas fluorescens, Pseudomonas fluorescens ACB
-
Manually annotated by BRENDA team
Moonen, M.J.; Kamerbeek, N.M.; Westphal, A.H.; Boeren, S.A.; Janssen, D.B.; Fraaije, M.W.; van Berkel, W.J.
Elucidation of the 4-hydroxyacetophenone catabolic pathway in Pseudomonas fluorescens ACB
J. Bacteriol.
190
5190-5198
2008
Pseudomonas fluorescens (Q93TJ5), Pseudomonas fluorescens, Pseudomonas fluorescens ACB (Q93TJ5), Pseudomonas fluorescens ACB
Manually annotated by BRENDA team
Rodriguez, C.; De Gonzalo, G.; Fraaije, M.W.; Gotor, V.
Enzymatic kinetic resolution of racemic ketones catalyzed by Baeyer-Villiger monooxygenases
Tetrahedron Asymmetry
18
1338-1344
2007
Pseudomonas fluorescens
-
Manually annotated by BRENDA team
Rehdorf, J.; Zimmer, C.L.; Bornscheuer, U.T.
Cloning, expression, characterization, and biocatalytic investigation of the 4-hydroxyacetophenone monooxygenase from Pseudomonas putida JD1
Appl. Environ. Microbiol.
75
3106-3114
2009
Pseudomonas putida (B7T912), Pseudomonas putida JD1 (B7T912), Pseudomonas putida JD1
Manually annotated by BRENDA team
Rioz-Martinez, A.; De Gonzal, D.G.; Torres Pazmino, D.; Fraaije, M.; Gotor, V.
Enzymatic Baeyer-Villiger oxidation of Benzo-Fused ketones: Formation of regiocomplementary lactones
Eur. J. Org. Chem.
15
2526-2532
2009
Pseudomonas fluorescens (Q93TJ5), Pseudomonas fluorescens ACB (Q93TJ5)
-
Manually annotated by BRENDA team
Rioz-Martinez, A.; De Gonzal, D.G.; Torres Pazmino, D.; Fraaije, M.; Gotor, V.
Enzymatic Baeyer-Villiger oxidation of benzo-fused ketones: Formation of regiocomplementary lactones
Eur. J. Org. Chem.
2009
2526-2532
2009
Pseudomonas fluorescens
-
Manually annotated by BRENDA team
Rioz-Martinez, A.; de Gonzalo, G.; Torres Pazmino, D.E.; Fraaije, M.W.; Gotor, V.
Synthesis of chiral 3-alkyl-3,4-dihydroisocoumarins by dynamic kinetic resolutions catalyzed by a Baeyer-Villiger monooxygenase
J. Org. Chem.
75
2073-2076
2010
Pseudomonas fluorescens, Pseudomonas fluorescens ACB
Manually annotated by BRENDA team