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EC 2.1.2.8 Details

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EC number

2.1.2.8

Accepted name

deoxycytidylate 5-hydroxymethyltransferase

Reaction

5,10-methylenetetrahydrofolate + H₂O + deoxycytidylate = tetrahydrofolate + 5-hydroxymethyldeoxycytidylate

Other name(s)

dCMP hydroxymethylase, d-cytidine 5′-monophosphate hydroxymethylase, deoxyCMP hydroxymethylase, deoxycytidylate hydroxymethylase, deoxycytidylic hydroxymethylase

Systematic name

5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase

CAS registry number

9012-68-4

History

created 1972

EC Tree

1 Oxidoreductases

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.2 Hydroxymethyl-, formyl- and related transferases

2.1.2.1 glycine hydroxymethyltransferase

2.1.2.2 phosphoribosylglycinamide formyltransferase 1

2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

2.1.2.4 glycine formimidoyltransferase

2.1.2.5 glutamate formimidoyltransferase

2.1.2.6 created 1965, deleted 1984

2.1.2.7 D-alanine 2-hydroxymethyltransferase

2.1.2.8 deoxycytidylate 5-hydroxymethyltransferase

2.1.2.9 methionyl-tRNA formyltransferase

2.1.2.10 aminomethyltransferase

2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase

2.1.2.12 created 1983, deleted 1984

2.1.2.13 UDP-4-amino-4-deoxy-L-arabinose formyltransferase

2.1.2.14 GDP-perosamine N-formyltransferase

2.1.3 Carboxy- and carbamoyltransferases

2.1.4 Amidinotransferases

2.1.5 Methylenetransferases

2.2 Transferring aldehyde or ketonic groups

2.3 Acyltransferases

2.4 Glycosyltransferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.6 Transferring nitrogenous groups

2.7 Transferring phosphorus-containing groups

2.8 Transferring sulfur-containing groups

2.9 Transferring selenium-containing groups

2.10 Transferring molybdenum- or tungsten-containing groups