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EC 3.1.21.6 Details

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EC number

3.1.21.6

Accepted name

CC-preferring endodeoxyribonuclease

Reaction

endonucleolytic cleavage to give 5′-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC

Other name(s)

Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease

CAS registry number

37211-67-9

Comment

Prefers CC sites in double-stranded circular and linear DNA. Greater affinity for double-stranded than single-stranded DNA. Produces nicks, generating double-stranded fragments with 5′- and/or 3′-protruding single-stranded tails. Requires magnesium ions for activity. The endonuclease from Chlorella-like green algae infected with NYs-1 virus 4[1] may be the same enzyme.

History

created 1999

EC Tree

1 Oxidoreductases

2 Transferases

3 Hydrolases

3.1 Acting on ester bonds

3.1.1 Carboxylic-ester hydrolases

3.1.2 Thioester hydrolases

3.1.3 Phosphoric-monoester hydrolases

3.1.4 Phosphoric-diester hydrolases

3.1.5 Triphosphoric-monoester hydrolases

3.1.6 Sulfuric-ester hydrolases

3.1.7 Diphosphoric-monoester hydrolases

3.1.8 Phosphoric-triester hydrolases

3.1.11 Exodeoxyribonucleases producing 5′-phosphomonoesters

3.1.12 Exodeoxyribonucleases producing 3′-phosphomonoesters

3.1.13 Exoribonucleases producing 5′-phosphomonoesters

3.1.14 Exoribonucleases producing 3'-phosphomonoesters

3.1.15 Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters

3.1.16 Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters

3.1.21 Endodeoxyribonucleases producing 5'-phosphomonoesters

3.1.21.1 deoxyribonuclease I

3.1.21.2 deoxyribonuclease IV

3.1.21.3 type I site-specific deoxyribonuclease

3.1.21.4 type II site-specific deoxyribonuclease

3.1.21.5 type III site-specific deoxyribonuclease

3.1.21.6 CC-preferring endodeoxyribonuclease

3.1.21.7 deoxyribonuclease V

3.1.21.8 T₄ deoxyribonuclease II

3.1.21.9 T₄ deoxyribonuclease IV

3.1.21.10 crossover junction endodeoxyribonuclease

3.1.22 Endodeoxyribonucleases producing 3'-phosphomonoesters

3.1.23 Site-specific endodeoxyribonucleases: cleavage is sequence specific (deleted sub-subclass)

3.1.24 Site specific endodeoxyribonucleases: cleavage is not sequence specific (deleted sub-subclass)

3.1.24.1 created 1978, modified 1982, deleted 1984

3.1.24.2 created 1978, modified 1982, deleted 1984

3.1.24.3 created 1978, modified 1982, deleted 1984

3.1.24.4 created 1978, modified 1982, deleted 1984

3.1.25 Site-specific endodeoxyribonucleases that are specific for altered bases

3.1.26 Endoribonucleases producing 5'-phosphomonoesters

3.1.27 Endoribonucleases producing 3'-phosphomonoesters

3.1.30 Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters

3.1.31 Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters

3.2 Glycosylases

3.3 Acting on ether bonds

3.4 Acting on peptide bonds (peptidases)

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.6 Acting on acid anhydrides

3.7 Acting on carbon-carbon bonds

3.8 Acting on halide bonds

3.9 Acting on phosphorus-nitrogen bonds

3.10 Acting on sulfur-nitrogen bonds

3.11 Acting on carbon-phosphorus bonds

3.12 Acting on sulfur-sulfur bonds

3.13 Acting on carbon-sulfur bonds