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EC 5.3.3.22 Details

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EC number

5.3.3.22

Accepted name

lutein isomerase

Reaction

lutein = meso-zeaxanthin

Other name(s)

RPE65 (gene name), meso-zeaxanthin isomerase

Systematic name

lutein Δ⁴-Δ⁵-isomerase

Comment

The enzyme is found in the retinal pigment epithelium (RPE) of vertebrates. It also has the activity of EC 3.1.1.64, retinoid isomerohydrolase.

History

created 2018

EC Tree

1 Oxidoreductases

2 Transferases

3 Hydrolases

3.1 Acting on ester bonds

3.2 Glycosylases

3.3 Acting on ether bonds

3.4 Acting on peptide bonds (peptidases)

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.6 Acting on acid anhydrides

3.7 Acting on carbon-carbon bonds

3.8 Acting on halide bonds

3.9 Acting on phosphorus-nitrogen bonds

3.10 Acting on sulfur-nitrogen bonds

3.11 Acting on carbon-phosphorus bonds

3.12 Acting on sulfur-sulfur bonds

3.13 Acting on carbon-sulfur bonds

4 Lyases

5 Isomerases

5.1 Racemases and epimerases

5.2 cis-trans-Isomerases

5.3 Intramolecular oxidoreductases

5.3.1 Interconverting aldoses and ketoses, and related compounds

5.3.2 Interconverting keto- and enol-groups

5.3.3 Transposing C=C bonds

5.3.3.1 steroid Δ-isomerase

5.3.3.2 isopentenyl-diphosphate Δ-isomerase

5.3.3.3 vinylacetyl-CoA Δ-isomerase

5.3.3.4 muconolactone Δ-isomerase

5.3.3.5 cholestenol Δ-isomerase

5.3.3.6 methylitaconate Δ-isomerase

5.3.3.7 aconitate Δ-isomerase

5.3.3.8 Δ³-Δ²-enoyl-CoA isomerase

5.3.3.9 prostaglandin-A₁ Δ-isomerase

5.3.3.10 5-carboxymethyl-2-hydroxymuconate Δ-isomerase

5.3.3.11 isopiperitenone Δ-isomerase

5.3.3.12 L-dopachrome isomerase

5.3.3.13 polyenoic fatty acid isomerase

5.3.3.14 trans-2-decenoyl-[acyl-carrier protein] isomerase

5.3.3.15 ascopyrone tautomerase

5.3.3.16 4-oxalomesaconate tautomerase

5.3.3.17 trans-2,3-dihydro-3-hydroxyanthranilate isomerase

5.3.3.18 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase

5.3.3.19 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate isomerase

5.3.3.20 2-hydroxyisobutanoyl-CoA mutase

5.3.3.21 Δ^3,5-Δ^2,4-dienoyl-CoA isomerase

5.3.3.22 lutein isomerase

5.3.3.23 S-methyl-5-thioribulose 1-phosphate isomerase

5.3.4 Transposing S-S bonds

5.3.99 Other intramolecular oxidoreductases

5.4 Intramolecular transferases

5.5 Intramolecular lyases

5.6 Isomerases altering macromolecular conformation

5.99 Other isomerases

6 Ligases

7 Translocases