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Information on EC 2.8.3.5 - 3-oxoacid CoA-transferase

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EC Tree
     2 Transferases
         2.8 Transferring sulfur-containing groups
             2.8.3 CoA-transferases
                2.8.3.5 3-oxoacid CoA-transferase
IUBMB Comments
Acetoacetate and, more slowly, 3-oxopropanoate, 3-oxopentanoate, 3-oxo-4-methylpentanoate or 3-oxohexanoate can act as acceptors; malonyl-CoA can act instead of succinyl-CoA.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
3-ketoacid CoA-transferase, 3-ketoacid coenzyme A transferase, 3-ketoacid coenzyme A-transferase, 3-oxo-CoA transferase, 3-oxoacid CoA dehydrogenase, 3-oxoacid CoA transferase 1, 3-oxoacid coenzyme A-transferase, acetoacetate succinyl-CoA transferase, acetoacetyl coenzyme A-succinic thiophorase, CoA transferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA
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