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Version 2014-12-22
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Details for C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
1.1.1.170, 1.1.1.-
Gene ontology ID
GO:0000252
Definition
Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H
Comment
Note that zymosterol is cholesta-8,24-dien-3-ol.
References
1. EC 1.1.1.170
2. PMID 9811880
3. EC 1.1.1.-
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