2.4.2.29: tRNA-guanosine34 preQ1 transglycosylase

This is an abbreviated version!
For detailed information about tRNA-guanosine34 preQ1 transglycosylase, go to the full flat file.

Word Map on EC 2.4.2.29

2.4.2.29

anticodon

queuosine

wobble

mobilis

trnatyr

shigella

zymomonas

hypermodified

archaeosine

shigellosis

preq0

trna-modifying

trnaasn

trnahis

7-cyano-7-deazaguanine

minihelix

7-deazaguanosine

garcia

medicine

Reaction

Synonyms

ArcTGT, guanine insertion enzyme, guanine, queuine-tRNA transglycosylase, Q-insertase, QTRT1, QueTGT, queuine insertase, queuine tRNA ribosyltransferase, queuine tRNA-ribosyltransferase, queuine tRNA-ribosyltransferase subunit 1, ribosyltransferase, queuine transfer ribonucleate, TGT, transfer ribonucleate glycosyltransferase, tRNA guanine transglycosidase, tRNA guanine transglycosylase, tRNA transglycosylase, tRNA-guanine 34 transglycosylase, tRNA-guanine transglycosylase, tRNA�guanine transglycosylase, virulence-associated protein VACC

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.2 Pentosyltransferases

2.4.2.29 tRNA-guanosine34 preQ1 transglycosylase

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Results	in table
34820	AA Sequence
1	Application
1	CAS Registry Number
8	Cloned(Commentary)
10	Crystallization (Commentary)
65	Disease/ Diagnostics
2	General Information
109	Inhibitors
4	kcat/KM [mM/s]
79	Ki Value [mM]
36	KM Value [mM]
2	Localization
2	Metals/Ions
14	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
39	Organism
2	Pathway
213	PDB ID
1	pH Optimum
1	pH Range
12	Protein Variants
7	Purification (Commentary)
1	Reaction
1	Reaction Type
38	Reference
8	Source Tissue
1	Specific Activity [micromol/min/mg]
34	Substrates and Products (Substrate)
5	Subunits
48	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
29	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 2.4.2.29 - tRNA-guanosine34 preQ1 transglycosylase

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2-amino-5-(fluoromethyl)pyrrolo[2,3-d]pyrimidin-4(3H)-one + tRNAguanine

guanine + tRNA2-amino-5-(fluoromethyl)pyrrolo[2,3-d]pyrimidin-4(3H)-one

Escherichia coli

2-amino-5-(fluoromethyl)pyrrolo[2,3-d]pyrimidin-4(3H)-one appears to partition between: 1. normal turnover, 2. inactivation, 3. an alternative processing to an unidentrified fluoride-released product

644935

7-(cyano)-7-deazaguanine + tRNAguanine

guanine + tRNA(7-(cyano)-7-deazaguanine)

Escherichia coli

644917

inserted 7-(cyano)-7-deazaguanine is located in the first position of the anticodon

644917

7-aminomethyl-7-carbaguanine + [RNAECYMA]-2'-deoxyguanine 34

guanine + [RNAECYMA]-2'-deoxy-pre Q1

Escherichia coli

TGT-RNA covalent intermediate

702263

7-aminomethyl-7-carbaguanine + [RNAECYMA]-guanine

guanine + [RNAECYMA]-pre Q1

Escherichia coli

hairpin RNA corresponding to the tRNAtyr anticodon stem-loop motif, TGT-RNA covalent intermediate

702263

7-aminomethyl-7-carbaguanine + [tRNA]-guanine

guanine + [tRNA]-pre Q1

2 entries

guanine + tRNAguanine

tRNAguanine + guanine

Escherichia coli

644917

guanine34 in tRNA + 7-aminomethyl-7-carbaguanine

7-aminomethyl-7-carbaguanine34 in tRNA + guanine

13 entries

guanine34 in tRNA + queuine

queuine34 in tRNA + guanine

2 entries

pre-queuine 0 + tRNA guanine

guanine + tRNA pre-queuine 0

Zymomonas mobilis

P28720

688390

pre-queuine 1 + virF minihelix RNA

Escherichia coli

P0A847

689250

pre-queuine 1 + virF mRNA

Escherichia coli

P0A847

TGT may modulate the translation of VirF via modification of the virF mRNA

689250

[tRNATyr]7-aminomethyl-7-carbaguanine + guanine

[tRNATyr]-guanine + 7-aminomethyl-7-carbaguanine

3 entries

additional information

4 entries