2.5.1.56: N-acetylneuraminate synthase
This is an abbreviated version!
For detailed information about N-acetylneuraminate synthase, go to the full flat file.
Word Map on EC 2.5.1.56
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2.5.1.56
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n-acetylmannosamine
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antifreeze
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mannac
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meningitidis
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polysialic
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neunacs
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neuroinvasive
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synthesis
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cmp-sialic
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2-epimerase
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ice-binding
- 2.5.1.56
- n-acetylmannosamine
-
antifreeze
- mannac
- meningitidis
-
polysialic
-
neunacs
-
neuroinvasive
- synthesis
-
cmp-sialic
-
2-epimerase
-
ice-binding
Reaction
Synonyms
(NANA) condensing enzyme, EC 4.1.3.19, N-acetylneuraminate lyase synthase, N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating), N-acetylneuraminic acid condensing enzyme, N-acetylneuraminic acid synthase, NANA condensing enzyme, NANA synthase, NANAS, NANS, NeuAc synthase, NeuB, NeuB1, NeuNAc synthase, NmeNANAS, sialic acid synthase, synthase, N-acetylneuraminate
ECTree
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Engineering
Engineering on EC 2.5.1.56 - N-acetylneuraminate synthase
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G133V
naturally occuring mutation of the enzyme causing impaired enzyme activity and the enzyme-deficiency phenotype
K131Q
naturally occuring mutation of the enzyme causing impaired enzyme activity and the enzyme-deficiency phenotype
P189L
naturally occuring mutation of the enzyme causing impaired enzyme activity and the enzyme-deficiency phenotype
Y188H
naturally occuring mutation of the enzyme causing impaired enzyme activity and the enzyme-deficiency phenotype
additional information
generation of a truncated variant of enzyme NANAS which lacks the C-terminal AFPL domain, G272Term by inserting a stop codon. The truncation is made at residue Gly272 prior to the linker region
additional information
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generation of a truncated variant of enzyme NANAS which lacks the C-terminal AFPL domain, G272Term by inserting a stop codon. The truncation is made at residue Gly272 prior to the linker region
additional information
-
generation of a truncated variant of enzyme NANAS which lacks the C-terminal AFPL domain, G272Term by inserting a stop codon. The truncation is made at residue Gly272 prior to the linker region
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