Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.6.1.19: 4-aminobutyrate-2-oxoglutarate transaminase

This is an abbreviated version!
For detailed information about 4-aminobutyrate-2-oxoglutarate transaminase, go to the full flat file.

Word Map on EC 2.6.1.19

Reaction

4-aminobutanoate
+
2-oxoglutarate
=
succinate semialdehyde
 +
L-glutamate

Synonyms

4-aminobutyrate aminotransferase, 4-aminobutyrate transaminase, 4-aminobutyrate-2-ketoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate aminotransferase, 4-aminobutyrate-2-oxoglutarate transaminase, 4-aminobutyric acid 2-ketoglutaric acid aminotransferase, 4-aminobutyric acid aminotransferase, ABAT, aminobutyrate aminotransferase, aminobutyrate transaminase, aminotransferase, aminobutyrate, argD, argD6803, argD7002, Atu3000, beta-alanine aminotransferase, beta-alanine transaminase, beta-alanine-oxoglutarate aminotransferase, beta-alanine-oxoglutarate transaminase, bioA, CG010_026395, CgGABA-AT, GABA aminotransferase, GABA transaminase, GABA transferase, GABA-2-oxoglutarate aminotransferase, GABA-2-oxoglutarate transaminase, GABA-alpha-ketoglutarate aminotransferase, GABA-alpha-ketoglutarate transaminase, GABA-alpha-ketoglutaric acid transaminase, GABA-alpha-oxoglutarate aminotransferase, GABA-AT, GABA-oxoglutarate aminotransferase, GABA-oxoglutarate transaminase, GABA-T, GABA-T1, GABA-T2, GABA-T3, GABA-TA, GABA-transaminase, GABA:2-oxoglutarate aminotransferase, GABAT, GabT, gamma-aminobutyrate aminotransaminase, gamma-aminobutyrate aminotransferase, gamma-aminobutyrate transaminase, gamma-aminobutyrate transaminases, gamma-aminobutyrate-alpha-ketoglutarate aminotransferase, gamma-aminobutyrate-alpha-ketoglutarate transaminase, gamma-aminobutyrate: GABA transaminase, gamma-aminobutyrate:alpha-oxoglutarate aminotransferase, gamma-aminobutyric acid aminotransferase, gamma-aminobutyric acid pyruvate transaminase, gamma-aminobutyric acid transaminase, gamma-aminobutyric acid-2-oxoglutarate transaminase, gamma-aminobutyric acid-alpha-ketoglutarate transaminase, gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase, gamma-aminobutyric transaminase, gatT, glutamate-succinic semialdehyde transaminase, homotaurine:2-oxoglutarate aminotransferase, MdGABA-T1, MdGABA-T2, More, NCgl0462, NCgl2515, Osl2, pollen-pistil incompatibility 2, Pop2, SkUga1p, slr1022

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.19 4-aminobutyrate-2-oxoglutarate transaminase

Substrates Products

Substrates Products on EC 2.6.1.19 - 4-aminobutyrate-2-oxoglutarate transaminase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(1R,4S)-4-amino-2-cyclopentene-1-carboxylic acid + 2-oxoglutarate
? + L-glutamate
show the reaction diagram
-
analogue of 4-aminobutanoate, vigabatrin
-
-
?
(4R)-4-amino-1-cyclopentene-1-carboxylic acid + 2-oxoglutarate
4-oxo-1-cyclopentene1-carboxylic acid + L-glutamate
show the reaction diagram
-
analogue of 4-aminobutanoate, vigabatrin
-
-
?
(R)-4-amino-3-fluorobutanoic acid
4-aminobut-2-enoic acid + HF
show the reaction diagram
-
-
-
?
(R,S)-4-amino-3-fluorobutanoic acid
4-aminobut-2-enoic acid + HF
show the reaction diagram
neither enantiomer is a substrate for transamination. The rate of elimination of HF from the (R)-enantiomer is at least 10 times greater than that for the (S)-enantiomer
-
-
?
(S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid + 2-oxoglutarate
4-oxo-4,5-dihydro-2-thiophenecarboxylic acid + L-glutamate
show the reaction diagram
-
mechanism-based inactivator that partly undergoes inactivation
-
-
?
1H-tetrazole-5-butanamine + 2-oxoglutarate
(1H-tetrazol-5-yl)-butyraldehyde + L-glutamate
show the reaction diagram
-
-
-
-
?
1H-tetrazole-5-ethanamine + 2-oxoglutarate
(1H-tetrazol-5-yl)-acetaldehyd + L-glutamate
show the reaction diagram
-
-
-
-
?
1H-tetrazole-5-propanamine + 2-oxoglutarate
(1H-tetrazol-5-yl)-propionaldehyde + L-glutamate
show the reaction diagram
-
-
-
-
?
3-(aminomethyl)benzoic acid + 2-oxoglutarate
3-(iminomethyl)benzoic acid + L-glutamate
show the reaction diagram
3.4% of the activity with 4-aminobutanoate
-
-
?
3-aminoisobutanoate + 2-oxoglutarate
L-glutamate + 3-oxoisobutanoate
show the reaction diagram
3-aminopropanesulfonate + 2-oxoglutarate
3-sulfopropanal + L-glutamate
show the reaction diagram
substrate is homotaurine
-
-
?
4-(aminomethyl)-1H-pyrrole-2-carboxylic acid + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
4-(aminomethyl)furan-2-carboxylic acid + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
4-(aminomethyl)furan-3-carboxylic acid + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
4-(aminomethyl)thiophene-2-carboxylic acid + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
4-(aminomethyl)thiophene-3-carboxylic acid + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
4-aminobutanoate + 2-oxoglutarate
4-oxobutanoate + L-glutamate
show the reaction diagram
4-aminobutanoate + 2-oxoglutarate
succinate semialdehyde + L-glutamate
show the reaction diagram
4-aminobutanoate + glyoxylate
4-oxobutanoate + glycine
show the reaction diagram
4-aminobutanoate + pyruvate
4-oxobutanoate + alanine
show the reaction diagram
4-aminobutanoate + pyruvate
4-oxobutanoate + L-alanine
show the reaction diagram
4-aminobutanoate + pyruvate
succinate semialdehyde + L-alanine
show the reaction diagram
4-aminobutyrate + 2-oxoglutarate
4-oxobutanoate + L-glutamate
show the reaction diagram
-
-
-
?
4-aminobutyrate + 2-oxoglutarate
succinic semialdehyde + L-glutamate
show the reaction diagram
5-(aminomethyl)-1H-pyrrole-2-carboxylic acid + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
5-(aminomethyl)furan-2-carboxylic acid + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
5-(aminomethyl)thiophene-2-carboxylic acid + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
5-aminopentanoate + 2-oxoglutarate
L-glutamate + 5-oxopentanoate
show the reaction diagram
5-aminovaleric acid + pyruvate
5-oxopentanoate + L-alanine
show the reaction diagram
6-aminohexanoate + 2-oxoglutarate
L-glutamate + 6-oxohexanoate
show the reaction diagram
beta-alanine + 2-oxoglutarate
malonic semialdehyde + L-glutamate
show the reaction diagram
cadaverine + 2-oxoglutarate
L-glutamate + 5-aminopentanal
show the reaction diagram
-
-
-
-
?
cadaverine + 2-oxoglutarate
L-glutamate + ?
show the reaction diagram
-
poor amino donor
-
-
r
D-lysine + 2-oxoglutarate
L-glutamate + 5-aminopentanal
show the reaction diagram
DL-3-amino-1-cyclopentene-1-carboxylic acid + 2-oxoglutarate
3-oxo-1-cyclopentene-1-carboxylic acid + L-glutamate
show the reaction diagram
-
analogue of 4-aminobutanoate, vigabatrin
-
-
?
DL-3-hydroxy-4-aminobutanoate + 2-oxoglutarate
L-glutamate + 3-hydroxy-4-oxobutanoate
show the reaction diagram
DL-ornithine + 2-oxoglutarate
L-glutamate + 4-methyl-2-oxopentanoate
show the reaction diagram
gamma-aminobutyric acid
?
show the reaction diagram
-
-
-
?
hypotaurine + 2-oxoglutarate
L-glutamate + 2-oxoethanesulfinic acid
show the reaction diagram
-
poor amino donor
-
-
r
L-3-aminoisobutanoate + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
L-lysine + 2-oxoglutarate
L-glutamate + (S)-2-amino-6-oxohexanoate
show the reaction diagram
-
-
i.e. L-2-aminoadipate-6-semialdehyde
-
?
L-ornithine + 2-oxoglutarate
L-glutamate + (S)-2-amino-5-oxopentanoate
show the reaction diagram
-
-
i.e. L-glutamate-gamma-semialdehyde
-
?
N2-acetyl-L-ornithine + 2-oxoglutarate
N-acetyl-L-glutamate 5-semialdehyde + L-glutamate
show the reaction diagram
putrescine + 2-oxoglutarate
L-glutamate + 4-aminobutanal
show the reaction diagram
tetrazole-5-butanamine + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
tetrazole-5-ethanamine + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
tetrazole-5-propanamine + 2-oxoglutarate
?
show the reaction diagram
-
-
-
-
?
[2-(aminomethyl)phenyl]acetic acid + 2-oxoglutarate
(2-formylphenyl)acetic acid + L-glutamate
show the reaction diagram
5.65% of the activity with 4-aminobutanoate
-
-
?
[3-(aminomethyl)phenyl]acetic acid + 2-oxoglutarate
(3-formylphenyl)acetic acid + L-glutamate
show the reaction diagram
0.78% of the activity with 4-aminobutanoate
-
-
?
additional information
?
-