2.7.1.71: shikimate kinase
This is an abbreviated version!
For detailed information about shikimate kinase, go to the full flat file.
Word Map on EC 2.7.1.71
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2.7.1.71
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chorismate
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shikimate-3-phosphate
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chrysanthemi
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oseltamivir
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dahp
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5-enolpyruvylshikimate
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3-deoxy-d-arabino-heptulosonate
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dehydroquinate
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7-phosphate
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drug development
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synthesis
- 2.7.1.71
- chorismate
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shikimate-3-phosphate
- chrysanthemi
- oseltamivir
- dahp
-
5-enolpyruvylshikimate
-
3-deoxy-d-arabino-heptulosonate
- dehydroquinate
- 7-phosphate
- drug development
- synthesis
Reaction
Synonyms
adenosine triphosphate: shikimate-3-phosphotransferase, AroK, AroL, AtSK1, AtSK2, kinase (phosphorylating), shikimate, kinase, shikimate (phosphorylating), MtSK, OsSK1, OsSK2, OsSK3, Rv2539c, shikimate kinase II, shikimate kinase-like 1, SK I, SK II, SK1, SK2, SKI, SKII, SKL1, type I shikimate kinase, aroK-encoded, type II shikimate kinase
ECTree
2.7.1.71 shikimate kinaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.7.1.71 - shikimate kinase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + shikimate
ADP + 3-phosphoshikimate
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-
-
-
?
ATP + shikimate
ADP + 3-phosphoshikimate
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specific phosphorylation of the 3-hydroxy group of shikimate
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-
?
ATP + shikimate
ADP + 3-phosphoshikimate
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-
-
?
ATP + shikimate
ADP + shikimate 3-phosphate
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-
-
-
?
ATP + shikimate
ADP + shikimate 3-phosphate
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SK2 is the isoenzyme that normally functions in aromatic biosynthesis in the cell, SK1 functions only when high intracellular levels of shikimate occurs
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?
ATP + shikimate
ADP + shikimate 3-phosphate
fifth step in the shikimate pathway
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-
?
ATP + shikimate
ADP + shikimate 3-phosphate
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the enzyme catalyzes the committed step in the seven-step biosynthesis of chorismate
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-
?
ATP + shikimate
ADP + shikimate 3-phosphate
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the substrate binds in a pocket lined with hydrophobic residues and interacts with several highly conserved charged residues including Asp34, Arg58,Glu61 and Arg136 which project into the cavity
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-
?
ATP + shikimate
ADP + shikimate 3-phosphate
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-
-
?
ATP + shikimate
ADP + shikimate 3-phosphate
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-
-
-
?
ATP + shikimate
ADP + shikimate 3-phosphate
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energy charge plays a role in regulating shikimate kinase, thereby controlling the shikimate pathway
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-
?
additional information
?
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AtSK2 shikimate binding residues include Gly177, Gly178, Gly179, and Asp130 of the Walker B motif and Phe146, Phe154, Glu158, Arg155, and Arg243
-
-
?
additional information
?
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-
AtSK2 shikimate binding residues include Gly177, Gly178, Gly179, and Asp130 of the Walker B motif and Phe146, Phe154, Glu158, Arg155, and Arg243
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-
?
additional information
?
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differential expression of the three rice SK genes OsSK1, OsSK2, and OsSK3, and the accompanying changes in the production of shikimate 3-phosphate may contribute to the defense response and to panicle development in rice
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-
?
additional information
?
-
differential expression of the three rice SK genes OsSK1, OsSK2, and OsSK3, and the accompanying changes in the production of shikimate 3-phosphate may contribute to the defense response and to panicle development in rice
-
-
?
additional information
?
-
differential expression of the three rice SK genes OsSK1, OsSK2, and OsSK3, and the accompanying changes in the production of shikimate 3-phosphate may contribute to the defense response and to panicle development in rice
-
-
?
additional information
?
-
-
differential expression of the three rice SK genes OsSK1, OsSK2, and OsSK3, and the accompanying changes in the production of shikimate 3-phosphate may contribute to the defense response and to panicle development in rice
-
-
?
additional information
?
-
differential expression of the three rice SK genes OsSK1,OsSK2, and OsSK3, and the accompanying changes in the production of shikimate 3-phosphate may contribute to the defense response and to panicle development in rice
-
-
?
additional information
?
-
differential expression of the three rice SK genes OsSK1,OsSK2, and OsSK3, and the accompanying changes in the production of shikimate 3-phosphate may contribute to the defense response and to panicle development in rice
-
-
?
additional information
?
-
differential expression of the three rice SK genes OsSK1,OsSK2, and OsSK3, and the accompanying changes in the production of shikimate 3-phosphate may contribute to the defense response and to panicle development in rice
-
-
?
additional information
?
-
-
differential expression of the three rice SK genes OsSK1,OsSK2, and OsSK3, and the accompanying changes in the production of shikimate 3-phosphate may contribute to the defense response and to panicle development in rice
-
-
?
additional information
?
-
-
no activity with XTP, ITP, GTP, TTP, CTP and UTP
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-
?
