1.1.1.282: quinate/shikimate dehydrogenase

This is an abbreviated version!
For detailed information about quinate/shikimate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.282

Reaction

L-quinate
+
NAD(P)+
=
3-dehydroquinate
+
NAD(P)H
+
H+

Synonyms

cgl0424, cgR_0495, dehydroquinate dehydratase-shikimate dehydrogenase, More, Poptr2, Poptr3, Poptr4, QSDH, qsuD, quinate/shikimate 5-dehydrogenase, quinate/shikimate dehydrogenase, rifI, RifI2, SDH, SDH/QDH, sdhL, shikimate/quinate dehydrogenase, YdiB

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.282 quinate/shikimate dehydrogenase

Engineering

Engineering on EC 1.1.1.282 - quinate/shikimate dehydrogenase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D107A
site-directed mutagenesis
K71G
site-directed mutagenesis
N92A
site-directed mutagenesis
Q262A
site-directed mutagenesis
S22A
site-directed mutagenesis
S67A
site-directed mutagenesis, increased activity compared to wild type enzyme
T106A
site-directed mutagenesis
Y39F
site-directed mutagenesis
N193D
site-directed mutagenesis, inactive mutant
N193L
site-directed mutagenesis, inactive mutant
N193Q
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
N193S
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
N193D
-
site-directed mutagenesis, inactive mutant
0
N193L
-
site-directed mutagenesis, inactive mutant
0
N193Q
-
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
0
N193S
-
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme
0
additional information