1.1.1.375: L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

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For detailed information about L-2-hydroxycarboxylate dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

Synonyms

lactate/malate dehydrogenase, LDH-like L-MalDH, MdhII, MJ0409, MJ0490

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

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Results

in table

1

Activating Compound

6

AA Sequence

2

Cloned(Commentary)

13

Cofactor

3

Crystallization (Commentary)

1

Inhibitors

13

KM Value [mM]

5

Metals/Ions

2

Molecular Weight [Da]

4

Natural Substrates/ Products (Substrates)

2

Organic Solvent Stability

21

Organism

1

Oxidation Stability

2

Pathway

4

pH Optimum

1

pH Range

4

Purification (Commentary)

1

Reaction

9

Reference

34

Substrates and Products (Substrate)

5

Subunits

16

Synonyms

1

Systematic Name

5

Temperature Optimum [�C]

1

Temperature Stability [�C]

Oxidation Stability

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Oxidation Stability on EC 1.1.1.375 - L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

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OXIDATION STABILITY

ORGANISM

UNIPROT

LITERATURE

the enzyme is not sensitive to oxygen

Methanocaldococcus jannaschii

Q60176

728317