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1.1.1.380: L-gulonate 5-dehydrogenase

This is an abbreviated version!
For detailed information about L-gulonate 5-dehydrogenase, go to the full flat file.

Reaction

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L-gulonate
+
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NAD+
=
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D-fructuronate
+
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NADH
+
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H+

Synonyms

HeGulDH, L-gulonate oxidoreductase, YjjN

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                EC 1.1.1.3801.1.1.380 L-gulonate 5-dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.380 - L-gulonate 5-dehydrogenase

for references in articles please use BRENDA:EC1.1.1.380

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
L-galactonate + NAD+
D-tagaturonate + NADH + H+
show the reaction diagram
preferred substrate
-
-
?
L-gulonate + NAD+
D-fructuronate + NADH + H+
show the reaction diagram
additional information
?
-
enzyme YjjN is an L-galactonate 5-dehydrogenase having activity also for L-gulonate. Reaction product identification by GC/MS analysis. No activity with substrates of similar structure, L-fuconate and L-lyxonate. And no activity with L-mannonate, L-rhamnonate, D-gulonate, D-galacturonate, D-glucuronate, D-gluconate, D-lyxonate, D-xylonate, D-ribonate, D-arabonate, D-mannonate, D-erythronate, D-glucose, D-xylitol, D-sorbitol, glucooctanic acid, and meso-galactarate. The hydroxyl group at the C6 seems to be essential for the activity
-
-
?