1.11.1.20: prostamide/prostaglandin F2alpha synthase
This is an abbreviated version!
For detailed information about prostamide/prostaglandin F2alpha synthase, go to the full flat file.
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Synonyms
PGF prostamide F synthase, PM/PGFS, Pmpgfs, prostaglandin F ethanolamide synthase, prostamide F synthase, prostamide/PGF synthase, prostamide/prostaglandin F synthase
ECTree
1.11.1.20 prostamide/prostaglandin F2alpha synthaseAdvanced search results
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Source Tissue on EC 1.11.1.20 - prostamide/prostaglandin F2alpha synthase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
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prostamide/PGF synthase is expressed preferentially in the white matter bundles of the entire central nervous system of adult mice with less marked expression in neuronal cell bodies
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the enzyme is colocalized with myelin basic protein in myelin sheaths but not in axons
activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs
activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs
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the enzyme is expressed preferentially in the white matter bundles of the entire central nervous system of adult mice with less marked expression in neuronal cell bodies. The enzyme is colocalized with myelin basic protein in myelin sheaths but not in axons. At the ultrastructural level, the enzyme is localized to myelin sheaths. Expression of the enzyme increases between postnatal day 9 and postnatal day 14 during the postnatal development, presumably in accordance with myelinogenesis
activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs
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cultured oligodendrocytes at 7 days in vitro express the enzyme in cytoplasmic processes where the enzyme is colocalized with myelin basic protein
activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs
localized in the superficial layer of the dorsal horn, in motor neurons of the ventral horn, and in glia of the white matter of the spinal cord. Activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs
activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs
activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs
activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs
activity is the highest in spinal cord and brain followed by thymus, adrenal gland, heart, and genital organs
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there is a tendency for the white matter bundles in the spinal cord, medulla oblongata, pons, and cerebellar medulla to express prostamide/PGF synthase more strongly than those in other central nervous system regions
