1.13.11.57: gallate dioxygenase

This is an abbreviated version!
For detailed information about gallate dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.57

Reaction

3,4,5-Trihydroxybenzoate
+
O2
=
(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate

Synonyms

DesB, GA dioxygenase, GALA

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.57 gallate dioxygenase

Crystallization

Crystallization on EC 1.13.11.57 - gallate dioxygenase

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CRYSTALLIZATION/commentary
ORGANISM
UNIPROT
LITERATURE
hanging drop vapor diffusion method, using 25% (w/v) PEG 8000, 0.1 M sodium acetate trihydrate, 0.1 M HEPES-NaOH pH 7.8, at 4C
-
crystallographic analyses of DesB shows that gallate is recognized by several hydrogen bonds. Three groups of the hydrogen bonds recognize a substrate and place the substrate in a productive arrangement