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1.13.11.85: exo-cleaving rubber dioxygenase

This is an abbreviated version!
For detailed information about exo-cleaving rubber dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.85

Reaction

cis-1,4-polyisoprene
+ n O2 = n (4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal

Synonyms

heme-dependent rubber oxygenase, LATA, poly(cis-1,4-isoprene)-cleavage enzyme, roxA, RoxB, RubA, rubber oxygenase, rubber oxygenase A

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.85 exo-cleaving rubber dioxygenase

Crystallization

Crystallization on EC 1.13.11.85 - exo-cleaving rubber dioxygenase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
to 1.8 A resolution. The enzyme shows an unusually low degree of secondary structure. RoxA incorporates both oxygen atoms of its cosubstrate dioxygen into the rubber cleavage product 12-oxo-4,8-dimethyl-trideca-4,8-diene-1-al
sitting drop vapor diffusion method, structural analysis of RoxA from Xanthomonas sp. strain 35Y at a resolution of 1.8 A
space group P2, unit cell parameters a = 72.4, b = 97.1, c = 101.1 A,beta 98.39°