1.2.1.107: glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring)
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For detailed information about glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring), go to the full flat file.
Reaction
Synonyms
acylglyceraldehyde-3-phosphate dehydrogenase, AsV reductase, D-glyceraldehyde-3-phosphate dehydrogenase, FA-GPDH, G3P dehydrogenase, G3PD, G3PDH, GAPDH, glyceraldehyde-3-P dehydrogenase, GPD, [beta-(2-furyl)acryloyl]glyceraldehyde-3-phosphate dehydrogenase
ECTree
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Inhibitors
Inhibitors on EC 1.2.1.107 - glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring)
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(S)-alpha-cholorhydrin
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100 or 200 mg/kg (S)-alpha-cholorhydrin inhibits arsenate reduction by the liver, but not by the whole body
arsenate
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the enzyme is allosterically inhibited at concentrations above 10 mM
L-Glyceraldehyde 3-phosphate
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the enzyme is allosterically inhibited at concentrations above 1 mM
D-glyceraldehyde 3-phosphate
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the enzyme is allosterically inhibited at concentrations above 1 mM
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the inhibition is competitive with respect to NAD+ and arsenate, but non-competitive with glyceraldehyde 3-phosphate
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Ghost band 3 polypeptide
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the inhibition is competitive with respect to NAD+ and arsenate, but non-competitive with glyceraldehyde 3-phosphate
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