1.2.1.48: long-chain-aldehyde dehydrogenase

This is an abbreviated version!
For detailed information about long-chain-aldehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.48

Reaction

a long-chain aldehyde
+
NAD+
+
H2O
=
a long-chain carboxylate
+
NADH
+ 2 H+

Synonyms

ALDH10, ALDH3A2, Aldh3b1, ALDH3B2, ALDH3B3, Bt-Aldh, dehydrogenase, long-chain aliphatic aldehyde, FALDH, fatty aldehyde dehydrogenase, fatty aldehyde:NAD+ oxidoreductase, long-chain aldehyde dehydrogenase, long-chain fatty aldehyde dehydrogenase, long-chain-aldehyde dehydrogenase, membrane-bound fatty aldehyde dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.48 long-chain-aldehyde dehydrogenase

Cloned

Cloned on EC 1.2.1.48 - long-chain-aldehyde dehydrogenase

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CLONED/commentary
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli
-
expressed in FAA-K1A cells
-
expression and overproduction in Escherichia coli; expression in Escherichia coli
gene ald1 cloned from the chromosomal DNA of the bacterium and expressed in Escherichia coli
-
gene ALDH3A2, recombinant expression of Strep-tagged enzyme in Escherichia coli, the enzyme lacks the predicted transmembrane alpha-helical region (residues 464-485) that is not included in the expression constructs, due to incompatibility with the protein production process
recombinant His6-FADH expressed in Escherichia coli BL21(DE3)
-