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1.2.1.49: 2-oxoaldehyde dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about 2-oxoaldehyde dehydrogenase (NADP+), go to the full flat file.

Reaction

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a 2-oxoaldehyde
+
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NADP+
+
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H2O
=
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a 2-oxo carboxylate
+
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NADPH
+
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H+

Synonyms

2-ketoaldehyde dehydrogenase, alpha-ketoaldehyde dehydrogenase, methylglyoxal dehydrogenase, NADP-dependent alpha-ketoaldehyde dehydrogenase, NADP-linked alpha-ketoaldehyde dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                EC 1.2.1.491.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.2.1.49 - 2-oxoaldehyde dehydrogenase (NADP+)

for references in articles please use BRENDA:EC1.2.1.49

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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY hide
Reversibility
r=reversible
ir=irreversible
?=not specified
2-keto-3-deoxy-D-glucose + NADP+ + H2O
2-keto-3-deoxy-D-gluconate + NADPH + H+
show the reaction diagram
-
Substrates: -
Products: -
r
2-keto-3-deoxy-D-glucose + NADP+ + H2O
2-keto-3-deoxy-D-gluconic acid + NADPH + H+
show the reaction diagram
2-oxoaldehydes + NADP+ + H2O
2-oxo acids + NADPH
show the reaction diagram
methylglyoxal + NADP+ + H2O
pyruvate + NADPH
show the reaction diagram
methylglyoxal + NADP+ + H2O
pyruvate + NADPH + H+
show the reaction diagram
additional information
?
-