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1.3.1.78: arogenate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about arogenate dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.3.1.78

Reaction

L-arogenate
+
NADP+
=
L-tyrosine
+
NADPH
+
CO2
+
H+

Synonyms

ADH1, ADH2, arogenate dehydrogenase, arogenate dehydrogenase isoform 1, arogenate dehydrogenase isoform 2, cyclohexadienyl dehydrogenase, TyrA arogenate dehydrogenase, TyrA1, TyrA2, TyrAa, TyrAAT, TyrAAT1, TyrAsy

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.78 arogenate dehydrogenase (NADP+)

Inhibitors

Inhibitors on EC 1.3.1.78 - arogenate dehydrogenase (NADP+)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
cis-aconitate
-
-
L-phenylalanine
-
slight inhibition
L-tyrosine
m-Fluoro-DL-tyrosine
-
-
N-Acetyl-DL-tyrosine
-
-
p-hydroxymercuribenzoate
prephenate
additional information
-
almost completely insensitive to feedback inhibition by tyrosine. Phenylalanine and tryptophan show no effect at concentrations of up to 1 mM
-