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1.3.8.12: (2S)-methylsuccinyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about (2S)-methylsuccinyl-CoA dehydrogenase, go to the full flat file.

Reaction

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(2S)-methylsuccinyl-CoA
+
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electron-transfer flavoprotein
=
Show molfile
2-methylfumaryl-CoA
+
Show molfile
reduced electron-transfer flavoprotein

Synonyms

MCD, methylsuccinyl-CoA dehydrogenase, PdMCD

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.8 With a flavin as acceptor
                EC 1.3.8.121.3.8.12 (2S)-methylsuccinyl-CoA dehydrogenase

Substrates Products

Substrates Products on EC 1.3.8.12 - (2S)-methylsuccinyl-CoA dehydrogenase

for references in articles please use BRENDA:EC1.3.8.12

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2S)-methylsuccinyl-CoA + electron-transfer flavoprotein
2-methylfumaryl-CoA + reduced electron-transfer flavoprotein
show the reaction diagram
(2S)-methylsuccinyl-CoA + ferrocenium hexafluorophosphate
mesaconyl-CoA + ferricenium hexafluorophosphate
show the reaction diagram
succinyl-CoA + electron-transfer flavoprotein
fumaryl-CoA + reduced electron-transfer flavoprotein
show the reaction diagram
succinyl-CoA + ferrocenium hexafluorophosphate
fumaryl-CoA + ferricenium hexafluorophosphate
show the reaction diagram
the enzyme shows about 0.5% activity with succinyl-CoA
-
-
?
additional information
?
-