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1.4.1.27: glycine cleavage system

This is an abbreviated version!
For detailed information about glycine cleavage system, go to the full flat file.

Word Map on EC 1.4.1.27

Reaction

glycine
+
tetrahydrofolate
+
NAD+
=
5,10-methylenetetrahydrofolate
+
NH3
+
CO2
+
NADH

Synonyms

Amt, At1g11860, At1g32470, At1g48030, AT2G35370, At4g33010, DLD, DLDH, GCSH, GCV, GcvH, GcvP, GCVT, GDCSH, GDCSP, GDH1, GDSCT, GLDC, glycine cleavage complex, H-protein, LpdA, P-protein, sll0171, slr1096, T-protein

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.27 glycine cleavage system

Source Tissue

Source Tissue on EC 1.4.1.27 - glycine cleavage system

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
in rat brain, the P-protein is confined to astrocytes. The intensity of astrocyte staining varies with regions, with the strongest staining in the hippocampus, the cerebellar cortex, the Bergmann glia in the cerebellum and the Muller cells in the retina
Manually annotated by BRENDA team
-
in rat brain, the P-protein is confined to astrocytes. The intensity of astrocyte staining varies with regions, with the strongest staining in the hippocampus, the cerebellar cortex, the Bergmann glia in the cerebellum and the Muller cells in the retina
Manually annotated by BRENDA team
-
P-protein mRNA is expressed mainly in glia-like cells, including Bergmann glias in the cerebellum, while T- and H-protein mRNAs are detected in both glial-like cells and neurons
Manually annotated by BRENDA team
-
in rat brain, the P-protein is confined to astrocytes. The intensity of astrocyte staining varies with regions, with the strongest staining in the hippocampus, the cerebellar cortex, the Bergmann glia in the cerebellum and the Muller cells in the retina
Manually annotated by BRENDA team
-
T- and H-protein mRNAs, but not P-protein mRNA, are expressed in the spinal cord
Manually annotated by BRENDA team