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1.4.3.14: L-lysine oxidase

This is an abbreviated version!
For detailed information about L-lysine oxidase, go to the full flat file.

Word Map on EC 1.4.3.14

Reaction

L-lysine
+
O2
+
H2O
=
6-Amino-2-oxohexanoate
+
NH3
+
H2O2

Synonyms

AIP, apoptosis-inducing protein, L-LOX/MOG, L-lysine alpha-oxidase, L-lysine oxidase/monooxygenase, L-lysine-a-oxidase, L-lysine-alpha-oxidase, L-lysyl-alpha-oxidase, L6150, LyOx, lysine-oxidase, LysOx

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.14 L-lysine oxidase

Cloned

Cloned on EC 1.4.3.14 - L-lysine oxidase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Pichia pastoris X-33 cells
-
expressed in Streptomyces lividans strain TK24
-
sequence comparisons, the enzyme shows 100% sequence identitiy with gene alpP of Pseudoalteromonas tunicata D2 encoding an autolytic and antibacterial protein
-
the enzyme (LysOX) is expressed in Streptomyces lividans TK24 and in Escherichia coli. The D212A, D315A, and D212A/D315A mutant variants are expressed in Escherichia coli
the L-lysine oxidase precursor prLysOX is overexpressed in Escherichia coli SoluBL21