1.8.98.2: sulfiredoxin

This is an abbreviated version!
For detailed information about sulfiredoxin, go to the full flat file.

Reaction

Synonyms

AtSrx, cysteine-sulfinic acid reductase, neoplastic progression 3, peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase, protein cysteine sulfinic acid reductase, Srx, Srx1, Srxn1, sulfiredoxin, sulfiredoxin 1, sulfiredoxin-1, sulphiredoxin

ECTree

     1 Oxidoreductases

         1.8 Acting on a sulfur group of donors

             1.8.98 With other, known, physiological acceptors

                1.8.98.2 sulfiredoxin

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1	Activating Compound
1793	AA Sequence
5	Application
1	CAS Registry Number
19	Cloned(Commentary)
17	Cofactor
4	Crystallization (Commentary)
228	Disease/ Diagnostics
8	Expression
18	General Information
2	IC50 Value
9	Inhibitors
8	KM Value [mM]
20	Localization
11	Metals/Ions
6	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
50	Organism
26	PDB ID
3	pH Optimum
3	pI Value
36	Protein Variants
9	Purification (Commentary)
1	Reaction
17	Reaction Type
44	Reference
40	Source Tissue
73	Substrates and Products (Substrate)
3	Subunits
54	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
5	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 1.8.98.2 - sulfiredoxin

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0067

4-(((4-(4-(2-chlorophenyl)piperazin-1-yl)-6-(2,4-dihydroxy-5-isopropylphenyl)pyrimidin-2-yl)thio)methyl)benzoic acid

Homo sapiens

Q9BYN0

against A549 cells, pH and temperature not specified in the publication

765246

-

0.0128

4-[[[4-[4-(2-chlorophenyl)-1-piperazinyl]-6-phenyl-2-pyrimidinyl]thio]methyl]-benzoic acid

Homo sapiens

Q9BYN0

against A549 cells, pH and temperature not specified in the publication

765246

-