1.8.99.2: adenylyl-sulfate reductase

This is an abbreviated version!
For detailed information about adenylyl-sulfate reductase, go to the full flat file.

Word Map on EC 1.8.99.2

Reaction

AMP
+
sulfite
+
acceptor
=
adenylyl sulfate
+
reduced acceptor

Synonyms

5'-adenylyl sulfate reductase, 5'-adenylylsulfate reductase, 5-adenylylsulfate reductase, AcAPR1, adenosine 5'-phosphosulfate reductase, adenosine phosphosulfate reductase, adenosine-5'-phosphosulfate reductase, adenylyl sulfate reductase, adenylylsulfate reductase, adenylylsulphate reductase, AdoPSO4 reductase, AMP,sulfite:flavin oxidoreductase, APR, APR1, APR2, APR3, AprA, AprB, AprBA, APS reductase, APS-reductase, APSR, AR, ATAPR2, Dde_1110, dissimilatory APS reductase, dissimilatory APS reductases, EAPR, EiAPR, FAD, FeS-enzyme adenosine-5'-phosphosulfate reductase, LMAPR, reductase, adenylylsulfate

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.99 With unknown physiological acceptors
                1.8.99.2 adenylyl-sulfate reductase

Engineering

Engineering on EC 1.8.99.2 - adenylyl-sulfate reductase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C139S
no detectable activity
C140S
reduced activity compared to wild type enzyme
C228S
reduced activity compared to wild type enzyme
C231S
reduced activity compared to wild type enzyme
C256S
reduced activity compared to wild type enzyme
C129S
-
maximal velocity dropps to 50% of that of the wild-type enzyme
C248S
-
mutation completely abolishes enzyme activity
C140S
-
the mutation has a deleterious effect on the amount of iron associated with the enzyme, no detectable catalytic activity
C141S
-
the mutation has a deleterious effect on the amount of iron associated with the enzyme, no detectable catalytic activity
C223S
-
the mutation has a deleterious effect on the amount of iron associated with the enzyme, no detectable catalytic activity
C226S
-
the mutation has a deleterious effect on the amount of iron associated with the enzyme, no detectable catalytic activity
C249S
C139S
C140S
C228S
C231S
C256S
C165S
reduced activity compared to wild type enzyme
C166S
reduced activity compared to wild type enzyme
C250S
reduced activity compared to wild type enzyme
C257S
reduced activity compared to wild type enzyme
C260S
reduced activity compared to wild type enzyme
C285S
reduced activity compared to wild type enzyme
C342S
reduced activity compared to wild type enzyme
C345S
reduced activity compared to wild type enzyme