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2.4.2.59: sulfide-dependent adenosine diphosphate thiazole synthase

This is an abbreviated version!
For detailed information about sulfide-dependent adenosine diphosphate thiazole synthase, go to the full flat file.

Reaction

NAD+
+
glycine
 +
Sulfide
=
nicotinamide
 +
ADP-5-ethyl-4-methylthiazole-2-carboxylate
 + 3 H2O

Synonyms

MJ0601, Thi4, thiamine thiazole synthase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.59 sulfide-dependent adenosine diphosphate thiazole synthase

Metals Ions

Metals Ions on EC 2.4.2.59 - sulfide-dependent adenosine diphosphate thiazole synthase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Ca2+
may substitute for iron
Co2+
may substitute for iron
Fe3+
highest levels of activity in presence of FE2+ or Fe3+, iron is involved in sulfur transfer
Mg2+
may substitute for iron
Mn2+
may substitute for iron
Ni2+
may substitute for iron
Zn2+
may substitute for iron
additional information
Cu+ or Cu2+ do not support activity