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Information on EC 1.14.13.9 - kynurenine 3-monooxygenase

for references in articles please use BRENDA:EC1.14.13.9

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IUBMB Comments

A flavoprotein (FAD).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
cinnabar, kmo, kynurenine 3-monooxygenase, kynurenine 3-hydroxylase, kynurenine hydroxylase, kynurenine monooxygenase, kynurenine-3-monooxygenase, pfkmo, kyn-ohase, nadph-dependent flavin monooxygenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-kynurenine + NADPH + H+ + O2 = 3-hydroxy-L-kynurenine + NADP+ + H2O
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
3-hydroxy-4-methyl-anthranilate biosynthesis I, 3-hydroxy-4-methyl-anthranilate biosynthesis II, L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde, L-tryptophan degradation XI (mammalian, via kynurenine)