2.1.3.2: aspartate carbamoyltransferase

This is an abbreviated version!
For detailed information about aspartate carbamoyltransferase, go to the full flat file.

Reaction

Synonyms

(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase, ACT, aspartate carbamoyltransferase, aspartate carbamyltransferase, aspartate trans carbamoylase, aspartate transcarbamoylase, aspartate transcarbamylase, aspartic acid transcarbamoylase, aspartic carbamyltransferase, aspartic transcarbamylase, ATC, ATC domain of CAD, ATCase, CAD, carbamoylaspartotranskinase, carbamoyltransferase, aspartate, carbamylaspartotranskinase, L-aspartate transcarbamoylase, L-aspartate transcarbamylase, MJ1581, PYRB

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.3 Carboxy- and carbamoyltransferases

                2.1.3.2 aspartate carbamoyltransferase

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Results	in table
60	Activating Compound
42879	AA Sequence
1	CAS Registry Number
28	Cloned(Commentary)
4	Cofactor
41	Crystallization (Commentary)
125	Disease/ Diagnostics
33	General Information
13	General Stability
18	IC50 Value
253	Inhibitors
66	Ki Value [mM]
77	KM Value [mM]
4	Localization
5	Metals/Ions
61	Molecular Weight [Da]
113	Natural Substrates/ Products (Substrates)
162	Organism
8	Pathway
316	PDB ID
24	pH Optimum
2	pH Range
3	pH Stability
1	Posttranslational Modification
61	Protein Variants
46	Purification (Commentary)
38	Reaction
2	Reaction Type
161	Reference
3	Renatured (Commentary)
36	Source Tissue
40	Specific Activity [micromol/min/mg]
9	Storage Stability
224	Substrates and Products (Substrate)
49	Subunits
104	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
3	Temperature Range [°C]
29	Temperature Stability [°C]
8	Turnover Number [1/s]

Organism

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Organism on EC 2.1.3.2 - aspartate carbamoyltransferase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Aquifex aeolicus

4 entries

Arabidopsis thaliana

-

663152, 689648

-

-

brenda

Azotobacter vinelandii

-

485837

-

-

brenda

Bacillus subtilis

2 entries

Citrobacter freundii

-

485837

-

-

brenda

Danio rerio

-

736000

-

-

brenda

Deinococcus radiophilus

-

690647

-

-

brenda

Drosophila melanogaster

-

485864

-

-

brenda

Eleusine coracana

-

485848

-

-

brenda

Enterococcus faecalis

-

485837, 485858, 485860, 485861

-

-

brenda

Escherichia coli

10 entries

Halobacterium salinarum

-

485837

-

-

brenda

Helicobacter pylori

-

485875

-

-

brenda

Homo sapiens

3 entries

Klebsiella aerogenes

-

485837

-

-

brenda

Lactuca sativa

-

485837

-

-

brenda

Lathyrus sativus

-

485848

-

-

brenda

Mesocricetus auratus

-

1734, 1735, 485845, 485852

-

-

brenda

Methanocaldococcus jannaschii

5 entries

Methanocaldococcus jannaschii DSM 2661

-

726566

Q58976

Uniprot

brenda

Moritella profunda

-

660619, 688339

-

-

brenda

Mus musculus

2 entries

Mya arenaria

-

661512, 661518

-

-

brenda

Mycolicibacterium smegmatis

-

485866

-

-

brenda

Mytilus edulis

mussel

485854

-

-

brenda

Neobodo saliens

-

684848

-

-

brenda

Neurospora crassa

-

485837

-

-

brenda

Oryctolagus cuniculus

-

485837

-

-

brenda

Pigeon

-

485836

-

-

brenda

Plasmodium falciparum

-

755726, 755966

O15804

UniProt

brenda

Pseudomonas aeruginosa

-

485837, 485886

-

-

brenda

Pseudomonas alcaligenes

-

662051

-

-

brenda

Pseudomonas fluorescens

-

485837, 485859, 485865

-

-

brenda

Pseudomonas mendocina

-

662051

-

-

brenda

Pseudomonas putida

biovar B

701171

-

-

brenda

Pseudomonas vulgaris

-

485837

-

-

brenda

Pyrococcus abyssi

3 entries

Pyrococcus furiosus

-

721560

-

-

brenda

Pyrococcus furiosus GE5

-

721560

-

-

brenda

Rattus norvegicus

-

1735, 485836, 485837

-

-

brenda

Saccharomyces cerevisiae

-

485837, 485880

-

-

brenda

Salmonella enterica subsp. enterica serovar Typhimurium

-

485837

-

-

brenda

Serratia marcescens

-

485837, 485877

-

-

brenda

Sulfolobus acidocaldarius

2 entries

Thermotoga maritima

-

748069

P96111

UniProt

brenda

Thermotoga maritima DSM 3109

-

748069

P96111

UniProt

brenda

Thermus thermophilus

-

736520

Q5SK66

UniProt

brenda

Thermus thermophilus HB8 / ATCC 27634 / DSM 579

-

736520

Q5SK66

UniProt

brenda

Trigonella foenum-graecum

-

485848

-

-

brenda

Triticum aestivum

2 entries

Trypanosoma cruzi

-

695390, 718755

-

-

brenda

Vibrio natriegens

-

485876

-

-

brenda

Vibrio sp.

isolated from the deep atlantic

485876

-

-

brenda

Vibrio sp. 2693

isolated from the deep atlantic

485876

-

-

brenda

Vigna radiata var. radiata

2 entries

Aquifex aeolicus

-

696352

O66726

UniProt

brenda

Aquifex aeolicus

-

737205

-

-

brenda

Aquifex aeolicus

expression in Escherichia coli

662173

-

-

brenda

Aquifex aeolicus

in noncovalent association with dihydroorotase, possible model for the mammalian polypeptide chain CPSase/ATCase/DHOase during pyrimidine biosynthesis

696352

O66726

UniProt

brenda

Bacillus subtilis

-

485837, 485849, 485857, 485872

-

-

brenda

Bacillus subtilis

-

720257

P05654

UniProt

brenda

Escherichia coli

-

485835, 485837, 485838, 485839, 485840, 485841, 485842, 485843, 485844, 485845, 485846, 485853, 485870, 485871, 485872, 485874, 485877, 485881, 485882

-

-

brenda

Escherichia coli

-

485883

P0A786

Uniprot

brenda

Escherichia coli

-

485884, 485885, 661140, 661272, 661450, 662222, 662627, 662646, 662651, 672392, 684138, 685252, 685568, 688367, 689777, 689963, 689977, 696699, 696763, 698488, 699559, 699578, 700959, 718458, 718699

-

-

brenda

Escherichia coli

-

718936, 718943

P0A786

Uniprot

brenda

Escherichia coli

-

720245

-

-

brenda

Escherichia coli

-

720943, 756715, 757003

P0A786

Uniprot

brenda

Escherichia coli

-

757536

-

-

brenda

Escherichia coli

-

758293

P0A786

Uniprot

brenda

Escherichia coli

gene pyrB

735674

P0A786

Uniprot

brenda

Escherichia coli

overexpression of enzyme

663253

-

-

brenda

Homo sapiens

-

735382

P27708

SwissProt

brenda

Homo sapiens

-

756715

-

-

brenda

Homo sapiens

-

758482

P27708

SwissProt

brenda

Methanocaldococcus jannaschii

-

485882

Q58976

Uniprot

brenda

Methanocaldococcus jannaschii

-

661272

-

-

brenda

Methanocaldococcus jannaschii

-

689946, 726566, 726604

Q58976

Uniprot

brenda

Methanocaldococcus jannaschii

catalytic subunit trimer

718518

Q58976

Uniprot

brenda

Methanocaldococcus jannaschii

regulatory subunit

718518

Q58801

UniProt

brenda

Mus musculus

-

485837, 485845, 736469, 757536

-

-

brenda

Mus musculus

Swiss albino

688051

-

-

brenda

Pyrococcus abyssi

-

485869

-

-

brenda

Pyrococcus abyssi

-

485887, 722614

P77918

Uniprot

brenda

Pyrococcus abyssi

recombinant protein

661693

-

-

brenda

Sulfolobus acidocaldarius

-

485879, 662624, 684926

-

-

brenda

Sulfolobus acidocaldarius

catalytic subunit PyrB

485879

Q55338

SwissProt

brenda

Triticum aestivum

-

485847, 485850, 485851, 485873, 485878

-

-

brenda

Triticum aestivum

wheat

485837

-

-

brenda

Vigna radiata var. radiata

-

485848, 485855, 485856, 485862, 485863

-

-

brenda

Vigna radiata var. radiata

mung bean

485837

-

-

brenda