2.4.2.1: purine-nucleoside phosphorylase

This is an abbreviated version!
For detailed information about purine-nucleoside phosphorylase, go to the full flat file.

Reaction

Synonyms

5'-deoxy-5'-methylthioadenosine phosphorylase II, 5'-methythioadenosine phosphorylase, adenine nucleoside phosphorylase, adenosine phosphorylase, AgPNP, AmPNP, ANP, ApMTAP, apPNP, bovPNP, bPNO, CKP1, cytokinin riboside phosphorylase, DeoD, deoD_1, DgPNP, EC592_06680, EcPNP, flB, GsPNPI, GsPNPII, GtPNP, hPNP, HpPNP, HsPNO, HsPNP, Ino-Guo phosphorylase, inosine phosphorylase, inosine-guanosine phosphorylase, KlacPNP, KLLA0_C16621g, MTAPII, MtbPNP, nucleotide phosphatase (2.4.2.1), PfPNP, phosphorylase, purine nucleoside, PiPNP, PNP, PNP 1, PNP 2, PNP I, PNP II, PNP-II, PNP-Zg, PNPase, pNPI, PNPII, Pu-NPase, punA, PUNP, PUNPI, PUNPII, purine deoxynucleoside phosphorylase, purine deoxyribonucleoside phosphorylase, purine nucleoside orthophosphate ribosyl transferase, purine nucleoside phosphorylase, purine nucleoside phosphorylase 1, purine nucleoside phosphorylase 2, purine nucleoside phosphorylase DeoD, purine nucleoside phosphorylase DeoD-type, purine nucleoside phosphorylase II, purine ribonucleoside phosphorylase, purine-nucleoside phosphorylases II, SalT, SSO2343, TgPNP, TTC0194, TTC1070, TtPNPI, TtPNPII, TvPNP, xanthosine phosphorylase, XAP, xapA, ylmD

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.1 purine-nucleoside phosphorylase

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Results	in table
6	Activating Compound
47462	AA Sequence
56	Application
1	CAS Registry Number
50	Cloned(Commentary)
60	Crystallization (Commentary)
3540	Disease/ Diagnostics
3	Expression
69	General Information
14	General Stability
108	IC50 Value
563	Inhibitors
135	kcat/KM [mM/s]
272	Ki Value [mM]
532	KM Value [mM]
6	Localization
2	Metals/Ions
109	Molecular Weight [Da]
145	Natural Substrates/ Products (Substrates)
7	Organic Solvent Stability
571	Organism
8	Oxidation Stability
22	Pathway
578	PDB ID
65	pH Optimum
12	pH Range
19	pH Stability
114	Protein Variants
74	Purification (Commentary)
20	Reaction
1	Reaction Type
364	Reference
2	Renatured (Commentary)
164	Source Tissue
105	Specific Activity [micromol/min/mg]
14	Storage Stability
924	Substrates and Products (Substrate)
107	Subunits
295	Synonyms
1	Systematic Name
39	Temperature Optimum [°C]
15	Temperature Range [°C]
71	Temperature Stability [°C]
259	Turnover Number [1/s]

Expression

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Expression on EC 2.4.2.1 - purine-nucleoside phosphorylase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

at early gastrula stage weak expression in lateral and ventral marginal zone, restricted expression from end of neurolation onward

Xenopus laevis

-

704082

Escherichia coli PNP-II (xanthosine phosphorylase) is inducible by xanthosine

Escherichia coli

P0ABP8, P45563

759101

high expression patterns at gastrulation in dorsal marginal region; at neurula stage strong expression in posterior region above the blastopore and in deep layer of neural plate

Xenopus laevis

-

704082