2.5.1.16: spermidine synthase

This is an abbreviated version!
For detailed information about spermidine synthase, go to the full flat file.

Reaction

Synonyms

aminopropyltransferase, aminopropyltransferase spermidine synthase, AtSPDS1, AtSPDS2, MdSPDS1, PAPT, PgSPD, putrescine aminopropyltransferase, Spd synthase, SPDS, SPDS2, SPDSYN, spe-sdh, spe3, SpeE, spermidine synthase, spermidine synthase 1, spermidine synthetase, Spm synthase, SpSyn, Synpcc7942_0628, synthase, spermidine

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.16 spermidine synthase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
2	Activating Compound
21026	AA Sequence
5	Application
1	CAS Registry Number
40	Cloned(Commentary)
4	Cofactor
14	Crystallization (Commentary)
93	Disease/ Diagnostics
2	Expression
30	General Information
14	General Stability
10	IC50 Value
198	Inhibitors
6	kcat/KM [mM/s]
10	Ki Value [mM]
51	KM Value [mM]
6	Localization
13	Metals/Ions
53	Molecular Weight [Da]
73	Natural Substrates/ Products (Substrates)
650	Organism
7	Pathway
196	PDB ID
27	pH Optimum
5	pH Range
4	pH Stability
2	pI Value
24	Protein Variants
42	Purification (Commentary)
15	Reaction
1	Reaction Type
125	Reference
118	Source Tissue
18	Specific Activity [micromol/min/mg]
18	Storage Stability
206	Substrates and Products (Substrate)
41	Subunits
80	Synonyms
1	Systematic Name
37	Temperature Optimum [°C]
4	Temperature Range [°C]
8	Temperature Stability [°C]
22	Turnover Number [1/s]

Application

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Application on EC 2.5.1.16 - spermidine synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Application Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

biotechnology

Cucurbita ficifolia

-

the FSPD1 gene is considered useful for gene transfer technology aiming at improving environmental stress tolerance of sweet potato

676402

drug development

Plasmodium falciparum

-

the enzyme is a drug target in the malaria parasite, Plasmodium falciparum, due to the vital role of spermidine in the activation of the eukaryotic translation initiation factor and cell proliferation

672560

medicine

2 entries

nutrition

Malus domestica

-

overexpression of the spermidine synthase gene substantially increases the tolerance to multiple stresses by altering the polyamine titers

690157

medicine

Leishmania donovani

-

pharmacologic inhibition of spermidine ssynthase, and perhaps all components of the polyamine biosynthetic pathway, is a valid therapeutic strategy for the treatment of visceral and, potentially, other forms of leishmaniasis

722385

medicine

Leishmania donovani LdBob

-

pharmacologic inhibition of spermidine ssynthase, and perhaps all components of the polyamine biosynthetic pathway, is a valid therapeutic strategy for the treatment of visceral and, potentially, other forms of leishmaniasis

-