2.7.4.8: guanylate kinase

This is an abbreviated version!
For detailed information about guanylate kinase, go to the full flat file.

Reaction

Synonyms

5'-GMP kinase, apo-EcGMPK, ATP: GMP phosphotransferase, ATP:GMP phosphotransferase, BmGK, CASK polypeptide, Cavbeta1b, Cavbeta2a, deoxyguanylate kinase, DLG1/SAP97, ecGMPK, GK, GK3, GKc, GKpm, GMK, GMK3, GMP kinase, GMPK, guanosine monophosphate kinase, guanosine monophosphate kinase (EcGMPK), guanylate kinase, guanylate kinase (GK), guanylate monophosphate kinase, GUK, kinase, guanylate (phosphorylating), MAGUK, MAGUK PSD-95, MAGUKs, membrane associated guanylate kinase, membrane associated guanylate kinase protein, membrane-associated guanylate kinase, membrane-associated guanylate kinases, MoGuk1, MoGuk2, More, organellar GK, post-synaptic density-95 membrane associated guanylate kinase, postsynaptic density protein-95 SH3 GK, PSD-95 GK, PSD-95 MAGUK, PSD-95alpha, PSD-95beta, Staphylococcus aureus guanylate monophosphate kinase, voltage-gated calcium channel beta1b, voltage-gated calcium channel beta2a, YGK

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.4 Phosphotransferases with a phosphate group as acceptor

                2.7.4.8 guanylate kinase

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Results	in table
2	Activating Compound
41441	AA Sequence
3	Application
1	CAS Registry Number
31	Cloned(Commentary)
11	Cofactor
12	Crystallization (Commentary)
296	Disease/ Diagnostics
2	Expression
34	General Information
8	General Stability
3	IC50 Value
78	Inhibitors
14	kcat/KM [mM/s]
23	Ki Value [mM]
86	KM Value [mM]
33	Localization
105	Metals/Ions
20	Molecular Weight [Da]
43	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
271	Organism
6	Pathway
83	PDB ID
19	pH Optimum
7	pH Range
3	pH Stability
4	pI Value
4	Posttranslational Modification
24	Protein Variants
37	Purification (Commentary)
4	Reaction
9	Reaction Type
76	Reference
3	Renatured (Commentary)
41	Source Tissue
21	Specific Activity [micromol/min/mg]
17	Storage Stability
217	Substrates and Products (Substrate)
15	Subunits
86	Synonyms
1	Systematic Name
20	Temperature Optimum [°C]
1	Temperature Range [°C]
15	Temperature Stability [°C]
28	Turnover Number [1/s]

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RENATURED/Commentary

ORGANISM

UNIPROT

LITERATURE

complete denaturation of the protein is not reversible due to aggregation at the unfolded state

Escherichia coli

P60546

662657

recombinant Cavbeta1b after overexpression in inclusion bodies in Xenopus laevis oocytes

Rattus norvegicus

Q8VGC3

700950

recombinant Cavbeta2a from inclusion bodies after overexpression in Xenopus laevis oocytes

Rattus norvegicus

Q8VGC3

700950