1.13.11.5: homogentisate 1,2-dioxygenase

This is an abbreviated version!
For detailed information about homogentisate 1,2-dioxygenase, go to the full flat file.

Word Map on EC 1.13.11.5

Reaction

homogentisate
+
O2
=
4-Maleylacetoacetate

Synonyms

EC 1.13.1.5, EC 1.99.2.5, ElHDO, HgD, HGDO, HGO, HGOa, HGOb, HmgA, homogentisate 1,2 dioxygenase, homogentisate 1,2-dioxygenase, homogentisate dioxygenase, homogentisate oxidase, homogentisate oxygenase, homogentisate phytyl-transferase, homogentisic acid 1,2-dioxygenase, homogentisic acid oxidase, homogentisic acid oxygenase, homogentisic oxygenase, homogentisicase, HPT, HTO

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.11 With incorporation of two atoms of oxygen
                1.13.11.5 homogentisate 1,2-dioxygenase

Specific Activity

Specific Activity on EC 1.13.11.5 - homogentisate 1,2-dioxygenase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0014
mutant enzyme I216T, pH and temperature not specified in the publication
0.0132
mutant enzyme W60G, pH and temperature not specified in the publication
0.023
mutant enzyme R225H, pH and temperature not specified in the publication
0.495
-
-
0.625
Agave toumeyana
-
-
0.7
mutant enzyme S189I, pH and temperature not specified in the publication
0.75 - 1
-
value in crude lysates
19.275
mutant enzyme H80Q, pH and temperature not specified in the publication
20.932
wild type enzyme, pH and temperature not specified in the publication
28.3
-
recombinant HGO
4.708
mutant enzyme Y62C, pH and temperature not specified in the publication
5.972
mutant enzyme E42A, pH and temperature not specified in the publication
6.842
mutant enzyme A122D, pH and temperature not specified in the publication
7.715
mutant enzyme M368V, pH and temperature not specified in the publication
additional information